Central hypothyroidism after chemotherapy in childhood cancer survivors: a single centre series
Sign Up to like & getrecommendations! Published in 2022 at "Acta Oncologica"
DOI: 10.1080/0284186x.2022.2156812
Abstract: Amy L. Wanaguru , Daniel J. Tait, Richard J. Cohn, Karen A. Johnston and Kristen A. Neville Department of Endocrinology, Sydney Children’s Hospital, Randwick, Australia; School of Paediatrics and Child Health, UNSW Sydney, Kensington, Australia;… read more here.
Keywords: hypothyroidism chemotherapy; central hypothyroidism; chemotherapy childhood; childhood cancer ... See more keywords
High Thyrotropin Is Critical for Cardiac Electrical Remodeling and Arrhythmia Vulnerability in Hypothyroidism
Sign Up to like & getrecommendations! Published in 2019 at "Thyroid"
DOI: 10.1089/thy.2018.0709
Abstract: Background: Hypothyroidism, the most common endocrine disease, induces cardiac electrical remodeling that creates a substrate for ventricular arrhythmias. Recent studies report that high thyrotropin (TSH) levels are related to cardiac electrical abnormalities and increased mortality… read more here.
Keywords: hypothyroidism; central hypothyroidism; tsh; high thyrotropin ... See more keywords
Central hypothyroidism with myxoedema: a less known but clinically challenging presentation
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2022-250282
Abstract: Myxoedema can have a variety of presentations, from mild cognitive impairment to psychosis, to overt coma. While majority of cases have primary hypothyroidism as the underlying aetiology, very few cases have central hypothyroidism. We report… read more here.
Keywords: less known; central hypothyroidism; myxoedema less; hypothyroidism myxoedema ... See more keywords
Detecting Congenital Central Hypothyroidism by Newborn Screening: Difficulty in Distinguishing from Congenital Thyroxine-Binding Globulin Deficiency
Sign Up to like & getrecommendations! Published in 2017 at "Hormone Research in Paediatrics"
DOI: 10.1159/000479367
Abstract: Background/Aims: Congenital central hypothyroidism (CH-C) can be detected on newborn screening (NBS) by programs using thyroxine (T4)-reflex thyroid-stimulating hormone (TSH) test approach. CH-C must be distinguished from T4-binding globulin (TBG) deficiency. We sought to determine… read more here.
Keywords: central hypothyroidism; congenital central; binding globulin; tbg deficiency ... See more keywords
Evaluation of the Optimal Thyroxine Levels for Thyroxine Hormone Replacement in Patients With Central Hypothyroidism
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvab048.1691
Abstract: Abstract Introduction: Central hypothyroidism results from pituitary or hypothalamic dysfunction. The evaluation of the adequacy of thyroxine replacement is difficult, due to the loss of thyrotropin (TSH) as an accurate feedback marker. This study aim… read more here.
Keywords: replacement; hypothyroidism; central hypothyroidism; ft4 ... See more keywords
Case Report: A Detailed Phenotypic Description of Patients and Relatives with Combined Central Hypothyroidism and Growth Hormone Deficiency Carrying IGSF1 Mutations
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DOI: 10.3390/genes13040623
Abstract: In recent years, variants in immunoglobulin superfamily member 1 (IGSF1) have been associated with congenital hypopituitarism. Initially, IGSF1 variants were only reported in patients with central hypothyroidism (CeH) and macroorchidism. Later on, IGSF1 variants were… read more here.
Keywords: hormone deficiency; report detailed; growth hormone; central hypothyroidism ... See more keywords