Chinese familial central precocious puberty with hyperuricemia due to recurrent DLK1 mutation: Case report and review of the literature
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DOI: 10.1002/mgg3.2087
Abstract: Central precocious puberty (CPP) is a precocious puberty due to premature activation of the hypothalamic–pituitary‐gonadal axis (HPG). MKRN3 defects are well‐known causes of CPP, while DLK1 mutations were recently identified in a few patients with… read more here.
Keywords: precocious puberty; central precocious; puberty; familial central ... See more keywords
MKRN3 levels in girls with central precocious puberty and correlation with sexual hormone levels: a pilot study
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DOI: 10.1007/s12020-017-1281-x
Abstract: PurposeRecently, mutations of makorin RING-finger protein 3 (MKRN3) have been described in familial central precocious puberty. Serum levels of this protein decline before the pubertal onset in healthy girls and boys. The aim of the… read more here.
Keywords: central precocious; study; precocious puberty; mkrn3 levels ... See more keywords
The first Japanese case of central precocious puberty with a novel MKRN3 mutation
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DOI: 10.1038/hgv.2017.17
Abstract: MKRN3, located on chromosome 15q11.2, encodes makorin ring-finger 3, which is an upstream suppressor of the hypothalamic-pituitary-gonadal axis. Mutation of this gene induces central precocious puberty (CPP). As MKRN3 is maternally imprinted, only the paternal… read more here.
Keywords: mkrn3; precocious puberty; first japanese; central precocious ... See more keywords
Comparison of triptorelin acetate vs triptorelin pamoate in the treatment of Central precocious puberty (CPP): a retrospective study
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DOI: 10.1080/09513590.2019.1655726
Abstract: Abstract The aim of this study is to compare the clinical and biochemical outcomes of triptorelin acetate (TPA) versus triptorelin pamoate (TPP) treatment in girls with central precocious puberty. A total of 60 patients with… read more here.
Keywords: triptorelin; triptorelin pamoate; central precocious; treatment ... See more keywords
Telomere length is not altered in girls with idiopathic central precocious puberty treated with a GnRH analog – leuprolide acetate
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DOI: 10.1080/09513590.2020.1770212
Abstract: Abstract Background Idiopathic central precocious puberty (iCPP) presents a disproportionate advancement of bone age and maturation, as well as metabolic and endocrinological changes that may be related to effects on telomere biology. Objective To investigate… read more here.
Keywords: idiopathic central; control; telomere length; central precocious ... See more keywords
Novel compound heterozygous mutations of PCNT gene in MOPD type II with central precocious puberty
Sign Up to like & getrecommendations! Published in 2020 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2020.1827382
Abstract: Abstract We report on a 6-year and 11-month old girl with short stature, microcephaly, proboscis nose, small teeth, left breast Tanner stage II, and nasopharynx adenoid hypertrophy. Her gestational age was 37 weeks and birth weight… read more here.
Keywords: precocious puberty; mutations pcnt; central precocious; pcnt gene ... See more keywords
Central precocious puberty: Recent advances in understanding the aetiology and in the clinical approach
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DOI: 10.1111/cen.14475
Abstract: Central precocious puberty (CPP) results from early activation of the hypothalamic‐pituitary‐gonadal (HPG) axis. The current state of knowledge of the complex neural network acting at the level of the hypothalamus and the GnRH neuron to… read more here.
Keywords: precocious puberty; puberty recent; central precocious; clinical approach ... See more keywords
Height benefit of GnRH agonists after age 8 in a Portuguese cohort of central precocious puberty
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DOI: 10.1111/cen.14884
Abstract: Idiopathic central precocious puberty (iCPP) is common in paediatric endocrinology. Gonadotropin‐releasing hormone agonists (GnRHa) are safe, but the effect on final height and the ideal timing for treatment remains controversial. This study aims to assess… read more here.
Keywords: height benefit; precocious puberty; central precocious; endocrinology ... See more keywords
Efficacy of Leuprorelin 3-Month Depot (11.25 mg) Compared to 1-Month Depot (3.75 mg) for Central Precocious Puberty in Chinese Girls: A Prospective Cohort Study
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DOI: 10.1155/2022/1043293
Abstract: Objective A 3-month depot of leuprorelin acetate (LA) was introduced in China in July 2020. However, the clinical experience is limited. The purpose of this study was to compare the efficacy of a LA 11.25 mg… read more here.
Keywords: study; central precocious; month; treatment ... See more keywords
Gene Polymorphisms Associated with Central Precocious Puberty and Hormone Levels in Chinese Girls
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DOI: 10.1155/2022/9450663
Abstract: Central precocious puberty (CPP) is associated with adverse health outcomes in females; however, CPP pathogenesis remains unclear. In this study, we investigated the association of 20 single nucleotide polymorphisms (SNPs) in eight genes with CPP… read more here.
Keywords: hormone levels; hormone; precocious puberty; central precocious ... See more keywords
Central precocious puberty in a girl with LEGIUS syndrome: an accidental association?
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DOI: 10.1186/s13052-021-01004-9
Abstract: Background Central precocious puberty is a condition characterized by precocious activation of the hypothalamic-pituitary-gonadal axis. It may be idiopathic or secondary to organic causes, including syndromes such as Neurofibromatosis type 1 (NF1). Case presentation We… read more here.
Keywords: precocious puberty; central precocious; puberty girl; girl legius ... See more keywords