Association of Central Sensitization Inventory Scores With Pain Outcomes After Endometriosis Surgery
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.0780
Abstract: Key Points Question Are greater Central Sensitization Inventory scores associated with worse pain outcomes after endometriosis surgery? Findings In this longitudinal presurgery and postsurgery cohort study of 239 people with endometriosis, higher Central Sensitization Inventory… read more here.
Keywords: central sensitization; sensitization inventory; inventory scores; pain outcomes ... See more keywords
Non‐Cyclical Mastalgia as a Central Sensitization Component: Implications for Multidisciplinary Treatment Approaches
Sign Up to like & getrecommendations! Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70962
Abstract: Non‐Cyclical mastalgia (NCM) is a chronic breast pain condition in women of reproductive age, often linked to anxiety and reduced quality of life (QoL). Evidence suggests central sensitization (CS) may contribute to NCM, but its… read more here.
Keywords: non cyclical; sensitization component; cyclical mastalgia; central sensitization ... See more keywords
Systematic review and co‐ordinate based meta‐analysis to summarize the utilization of functional brain imaging in conjunction with human models of peripheral and central sensitization
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Pain"
DOI: 10.1002/ejp.2251
Abstract: Functional magnetic resonance imaging, in conjunction with models of peripheral and/or central sensitization, has been used to assess analgesic efficacy in healthy humans. This review aims to summarize the use of these techniques to characterize… read more here.
Keywords: imaging conjunction; peripheral central; central sensitization; models peripheral ... See more keywords
Central sensitization inventory is associated with psychological functioning but not with psychophysical assessment of pain amplification
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Pain"
DOI: 10.1002/ejp.4713
Abstract: The central sensitization inventory (CSI) is a questionnaire that has been widely used as a tool for assessing symptoms associated with sensitization. However, its ability to identify individuals with this phenomenon has recently been questioned.… read more here.
Keywords: sensitization; pain; central sensitization; sensitization inventory ... See more keywords
Black box in overactive bladder: Central sensitization and its relationship with urinary symptom severity and quality of life
Sign Up to like & getrecommendations! Published in 2024 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.25394
Abstract: To examine central sensitization (CS), and to investigate the relationship between CS, and urinary symptom severity, and quality of life (QoL) in women with overactive bladder (OAB). read more here.
Keywords: urinary symptom; severity quality; central sensitization; quality life ... See more keywords
Aquaporin 4 knockout increases complete freund's adjuvant-induced spinal central sensitization
Sign Up to like & getrecommendations! Published in 2020 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2020.01.004
Abstract: Growing evidence suggests a critical role of astrocytes for pain regulation. The water channel protein aquaporin 4 (AQP4), a functional regulator of astrocytes, is involved in various neurological disorders. However, the pathophysiological roles of AQP4… read more here.
Keywords: spinal central; central sensitization; complete freund; induced spinal ... See more keywords
The focus of spatial attention during the induction of central sensitization can modulate the subsequent development of secondary hyperalgesia
Sign Up to like & getrecommendations! Published in 2020 at "Cortex"
DOI: 10.1016/j.cortex.2019.11.014
Abstract: Intense or sustained activation of peripheral nociceptors can induce central sensitization. This enhanced responsiveness to nociceptive input of the central nervous system primarily manifests as an increased sensitivity to painful mechanical pinprick stimuli extending beyond… read more here.
Keywords: spatial attention; secondary hyperalgesia; central sensitization; hyperalgesia ... See more keywords
Inhibition of interleukin-6 function attenuates the central sensitization and pain behavior induced by osteoarthritis.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2017.06.032
Abstract: Chronic pain is the most prominent and disabling symptom in the patients with osteoarthritis (OA), and the underlying mechanism largely remains unclear. Interleukin-6 (IL-6), a proinflammatory cytokine, is critically involved in the development and maintenance… read more here.
Keywords: dorsal horn; central sensitization; chronic pain; pain ... See more keywords
Complete spinal cord injury (SCI) transforms how brain derived neurotrophic factor (BDNF) affects nociceptive sensitization
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2016.11.001
Abstract: ABSTRACT Noxious stimulation can induce a lasting increase in neural excitability within the spinal cord (central sensitization) that can promote pain and disrupt adaptive function (maladaptive plasticity). Brain‐derived neurotrophic factor (BDNF) is known to regulate… read more here.
Keywords: sci; central sensitization; bdnf affects; bdnf ... See more keywords
Transient inhibition of LIMKs significantly attenuated central sensitization and delayed the development of chronic pain
Sign Up to like & getrecommendations! Published in 2017 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2017.06.031
Abstract: Central sensitization represents a key mechanism mediating chronic pain, a major clinical problem lacking effective treatment options. LIM-domain kinases (LIMKs) selectively regulate several substrates, e.g. cofilin and cAMP response element-binding protein (CREB), that profoundly affect… read more here.
Keywords: central sensitization; chronic pain; inhibition limks; development ... See more keywords
ERK potentiates p38 in central sensitization induced by traumatic occlusion
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2016.11.012
Abstract: This study was to investigate the role of p38 activation via ERK1/2 phosphorylation in neurons and microglia of the spinal trigeminal subnucleus caudalis (Vc) in the promotion of orofacial hyperalgesia induced by unilateral anterior crossbite… read more here.
Keywords: central sensitization; hyperalgesia; p38; traumatic occlusion ... See more keywords