Breakdown of the central synapses in C9orf72-linked ALS/FTD
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.1005112
Abstract: Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disease that leads to the death of motor and cortical neurons. The clinical manifestations of ALS are heterogenous, and efficacious treatments to significantly slow the progression… read more here.
Keywords: synapses c9orf72; c9orf72 linked; disease; breakdown central ... See more keywords
Similarity and Diversity of Presynaptic Molecules at Neuromuscular Junctions and Central Synapses
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12020179
Abstract: Synaptic transmission is essential for controlling motor functions and maintaining brain functions such as walking, breathing, cognition, learning, and memory. Neurotransmitter release is regulated by presynaptic molecules assembled in active zones of presynaptic terminals. The… read more here.
Keywords: presynaptic molecules; diversity presynaptic; neuromuscular junctions; similarity diversity ... See more keywords