Locus revealed: Painlessness via loss of NaV1.7 at central terminals of sensory neurons
Sign Up to like & getrecommendations! Published in 2021 at "Neuron"
DOI: 10.1016/j.neuron.2021.04.011
Abstract: How genetic loss of the sodium channel NaV1.7 results in painlessness is puzzling. MacDonald et al. (2021) demonstrate that instead of impairing peripheral excitability, NaV1.7 channels at central terminals of pain-sensing afferents play a pivotal role… read more here.
Keywords: central terminals; locus revealed; via loss; revealed painlessness ... See more keywords