Centromere and its associated proteins—what we know about them in Plasmodium falciparum
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DOI: 10.1002/iub.1878
Abstract: The complex life cycle of intracellular parasitic protozoans entails multiple rounds of DNA replication and mitosis followed by cytokinesis to release daughter parasites. To gain insights into mitotic events it is imperative to identify the… read more here.
Keywords: centromere associated; associated proteins; falciparum; plasmodium falciparum ... See more keywords
A non-canonical function for Centromere-associated protein-E controls centrosome integrity and orientation of cell division
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DOI: 10.1038/s42003-021-01861-4
Abstract: Centromere-associated protein-E (CENP-E) is a kinesin motor localizing at kinetochores. Although its mitotic functions have been well studied, it has been challenging to investigate direct consequences of CENP-E removal using conventional methods because CENP-E depletion… read more here.
Keywords: associated protein; centromere associated; cenp; cell division ... See more keywords
A comprehensive investigation on pan-cancer impacts of constitutive centromere associated network gene family by integrating multi-omics data
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DOI: 10.1097/md.0000000000028821
Abstract: Abstract Background: The constitutive centromere associated network (CCAN) complex played a critical role in connecting the centromere with the mitotic spindle during mitosis and meiosis. Many studies have indicated that CCAN is related to the… read more here.
Keywords: constitutive centromere; associated network; cancer; centromere associated ... See more keywords
Mitotic Centromere-Associated Kinesin (MCAK/KIF2C) Regulates Cell Migration and Invasion by Modulating Microtubule Dynamics and Focal Adhesion Turnover
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DOI: 10.3390/cancers13225673
Abstract: Simple Summary The microtubule (MT) cytoskeleton is a crucial factor for organized cell motility and migration of cancer as well as benign cells. Mitotic centromere-associated kinesin (MCAK/KIF2C) is a member of the kinesin-13 family, which… read more here.
Keywords: centromere associated; mcak; migration; kinesin ... See more keywords