Distinct Aurora B pools at the inner centromere and kinetochore have different contributions to meiotic and mitotic chromosome segregation.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular biology of the cell"
DOI: 10.1091/mbc.e23-01-0014
Abstract: Proper chromosome segregation depends on establishment of bioriented kinetochore-microtubule attachments, which often requires multiple rounds of release and reattachment. Aurora B and C kinases phosphorylate kinetochore proteins to release tensionless attachments. Multiple pathways recruit Aurora… read more here.
Keywords: aurora; kinetochore; chromosome segregation; centromere kinetochore ... See more keywords
Division of labour between PP2A-B56 isoforms at the centromere and kinetochore
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.42619
Abstract: PP2A-B56 is a serine/threonine phosphatase complex that regulates several major mitotic processes, including sister chromatid cohesion, kinetochore-microtubule attachment and the spindle assembly checkpoint. We show here that these key functions are divided between different B56… read more here.
Keywords: b56; pp2a b56; b56 isoforms; centromere kinetochore ... See more keywords