A Stable, Autonomously Replicating Plasmid Vector Containing Pichia pastoris Centromeric DNA
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DOI: 10.1128/aem.02882-17
Abstract: Secretory production of recombinant proteins is the most important application of the methylotrophic yeast Pichia pastoris, a species that permits mass production of heterologous proteins. To date, the genetic engineering of P. pastoris has relied… read more here.
Keywords: plasmid vector; autonomously replicating; centromeric dna; pastoris ... See more keywords
Enrichment of centromeric DNA from human cells
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DOI: 10.1371/journal.pgen.1010306
Abstract: Centromeres are key elements for chromosome segregation. Canonical centromeres are built over long-stretches of tandem repetitive arrays. Despite being quite abundant compared to other loci, centromere sequences overall still represent only 2 to 5% of… read more here.
Keywords: dna; dna human; centromeric dna; human cells ... See more keywords