Structure of the Human Core Centromeric Nucleosome Complex
Sign Up to like & getrecommendations! Published in 2019 at "Current Biology"
DOI: 10.1016/j.cub.2019.06.062
Abstract: Centromeric nucleosomes are at the interface of the chromosome and the kinetochore that connects to spindle microtubules in mitosis. The core centromeric nucleosome complex (CCNC) harbors the histone H3 variant, CENP-A, and its binding proteins, CENP-C… read more here.
Keywords: cenp; nucleosome complex; centromeric nucleosome; core centromeric ... See more keywords
Cryoelectron Microscopy Structure of a Yeast Centromeric Nucleosome at 2.7 Å Resolution.
Sign Up to like & getrecommendations! Published in 2020 at "Structure"
DOI: 10.1016/j.str.2019.12.002
Abstract: Kinetochores mediate chromosome segregation during cell division. They assemble on centromeric nucleosomes and capture spindle microtubules. In budding yeast, a kinetochore links a single nucleosome, containing the histone variant Cse4CENP-A instead of H3, with a… read more here.
Keywords: yeast centromeric; microscopy; cryoelectron microscopy; centromeric nucleosome ... See more keywords
Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N
Sign Up to like & getrecommendations! Published in 2018 at "Science"
DOI: 10.1126/science.aar2781
Abstract: Recognizing centromere by kinetochore The kinetochore proteins CENP-N and CENP-C recognize the histone H3 variant CENP-A in the centromeric nucleosome. This ensures proper kinetochore assembly and accurate segregation of chromosomes. Chittori et al. describe the… read more here.
Keywords: microscopy; centromeric nucleosome; cenp; cenp cenp ... See more keywords