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Published in 2018 at "Developmental cell"
DOI: 10.1016/j.devcel.2018.04.016
Abstract: Structural centrosomal aberrations have long been described in cancer, but their impact on cell physiology and tumorigenesis remains unclear. Ganier et al. (2018) show that centrosome structural abnormalities facilitate cell dissemination by promoting budding of epithelial…
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Keywords:
abnormalities push;
structural centrosomal;
push cells;
cells toward ... See more keywords
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Published in 2018 at "Anticancer research"
DOI: 10.21873/anticanres.12345
Abstract: The centrosome is the main microtubule-organizing center in human cells. It regulates normal cell-cycle progression and cell division. Aberrations in the number, structure and function of centrosomes have been found to drive genomic instability and…
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Keywords:
pancreatic cancer;
centrosomal abnormalities;
molecular mechanisms;
abnormalities pancreatic ... See more keywords