Genetic interaction between PLK1 and downstream MCPH proteins in the control of centrosome asymmetry and cell fate during neural progenitor division.
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DOI: 10.1038/s41418-022-00937-w
Abstract: Alteration of centrosome function and dynamics results in major defects during chromosome segregation and is associated with primary autosomal microcephaly (MCPH). Despite the knowledge accumulated in the last few years, why some centrosomal defects specifically… read more here.
Keywords: asymmetry cell; neural progenitors; plk1; mcph ... See more keywords