Abstract 1825: Tumor-targeted knockdown of KRAS mutants with novel Centyrin:siRNA conjugates
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DOI: 10.1158/1538-7445.am2020-1825
Abstract: KRAS has been the quintessential undruggable oncogene for many years. Although there have been recently described small molecule inhibitors of KRAS, these molecules only target a specific mutant form, KRAS G12C. The KRAS G12C mutation… read more here.
Keywords: centyrin; centyrin sirna; knockdown kras; kras mutants ... See more keywords