Somatic Niche Cells Regulate the CEP-1/p53-Mediated DNA Damage Response in Primordial Germ Cells.
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DOI: 10.1016/j.devcel.2019.06.012
Abstract: Genome integrity in primordial germ cells (PGCs) is a prerequisite for fertility and species maintenance. In C. elegans, PGCs require global-genome nucleotide excision repair (GG-NER) to remove UV-induced DNA lesions. Failure to remove the lesions leads… read more here.
Keywords: cep p53; dna damage; p53 mediated; mediated dna ... See more keywords