Requirement of the Cep57-Cep63 Interaction for Proper Cep152 Recruitment and Centriole Duplication
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00535-19
Abstract: Cep57 has been characterized as a component of a pericentriolar complex containing Cep63 and Cep152. Interestingly, Cep63 and Cep152 self-assemble into a pericentriolar cylindrical architecture, and this event is critical for the orderly recruitment of… read more here.
Keywords: cep63 cep152; cep57 cep63; cep152; recruitment ... See more keywords
Expression Analyses of Cep152, a Responsible Gene Product for Autosomal Recessive Primary Microcephaly, during Mouse Brain Development
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Neuroscience"
DOI: 10.1159/000523922
Abstract: Centrosomal protein 152 (Cep152) regulates centriole duplication as a molecular scaffold during the cell cycle. Its gene abnormalities are responsible for autosomal recessive primary microcephaly 9 and Seckel syndrome. In this study, we prepared an… read more here.
Keywords: brain development; cep152; autosomal recessive; recessive primary ... See more keywords
Cep57 and Cep57l1 function redundantly to recruit the Cep63–Cep152 complex for centriole biogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.241836
Abstract: ABSTRACT The Cep63–Cep152 complex located at the mother centriole recruits Plk4 to initiate centriole biogenesis. How the complex is targeted to mother centrioles, however, is unclear. In this study, we show that Cep57 and its… read more here.
Keywords: cep152; cep152 complex; cep63 cep152; cep57 cep57l1 ... See more keywords