Mechanism of Centrosomal Protein 55 (CEP55) Loading Into Exosomes
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.70046
Abstract: ABSTRACT Up‐regulation of Centrosomal Protein 55 (CEP55) in cancer cells increases malignancy, and the protein can be transferred via exosomes. However, the mechanism of how CEP55 is delivered to exosomes is unknown. In this study,… read more here.
Keywords: protein cep55; cep55 loading; protein; mechanism centrosomal ... See more keywords
CEP55 promoted the migration, invasion and neuroshpere formation of the glioma cell line U251
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.04.038
Abstract: Glioma stem cells (GSC) were important for Glioblastoma (GBM) initiation and chemotherapy resistance. Centrosomal protein of 55 kDa (CEP55) was a biomarker for multiple cancers. However, roles and mechanism of CEP55 in glioma tumorigenesis and stemness… read more here.
Keywords: glioma; invasion; cep55; like cells ... See more keywords
Long intergenic non-protein coding RNA 662 accelerates the progression of gastric cancer through up-regulating centrosomal protein 55 by sponging microRNA-195-5p
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2023978
Abstract: ABSTRACT Long non-coding RNAs (lncRNAs) are important players in regulating diverse human diseases, including cancers. Nonetheless, the function of long intergenic non-protein coding RNA 662 (LINC00662) in gastric cancer (GC) carcinogenesis and progression remains to… read more here.
Keywords: non protein; long intergenic; cep55; intergenic non ... See more keywords
Strategic inhibition of CEP55 in aggressive breast cancer leads to mitotic catastrophe
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz238.001
Abstract: Abstract Background Triple negative breast cancers (TNBCs), with negligible ER, PR expression and HER2 amplification are the most aggressive form of breast cancer (BC). Due to the high level of genomic instability, treatment of TNBC… read more here.
Keywords: breast; cep55; inhibition; breast cancer ... See more keywords
Abstract B28: Cep55 regulates YAP/TAZ expression and localization during cell cycle progression
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Cancer Research"
DOI: 10.1158/1557-3125.hippo19-b28
Abstract: Cell cycle regulation plays a pivotal role in controlling cell proliferation and survival. Aberrant expression of cell cycle-associated genes generally afflicts cells with tumor-prone characteristics and promotes chromosome instability. Cep55 (Centrosome Protein 55kDa; also known… read more here.
Keywords: yap taz; cep55; expression; cell cycle ... See more keywords
CEP55 as a promising biomarker and therapeutic target on gallbladder cancer
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1156177
Abstract: Introduction Gallbladder cancer (GBC) is a highly malignant biliary tumor with a poor prognosis. As existing therapies for advanced metastatic GBC are rarely effective, there is an urgent need to identify more effective targets for… read more here.
Keywords: cep55; target; gbc; gallbladder cancer ... See more keywords
Centrosomal Protein 55 (CEP55) Drives Immune Exclusion and Resistance to Immune Checkpoint Inhibitors in Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2024 at "Vaccines"
DOI: 10.3390/vaccines12010063
Abstract: Colorectal cancer (CRC) currently ranks as the third most common cancer in the United States, and its incidence is on the rise, especially among younger individuals. Despite the remarkable success of immune checkpoint inhibitors (ICIs)… read more here.
Keywords: cancer; immune checkpoint; crc; immune exclusion ... See more keywords
Overexpression of centrosomal protein 55 regulates the proliferation of glioma cell and mediates proliferation promoted by EGFRvIII in glioblastoma U251 cells.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology letters"
DOI: 10.3892/ol.2017.7573
Abstract: The epidermal growth factor receptor (EGFR) is often amplified in glioma, with the most common extracellular domain mutation being EGFR variant III (EGFRvIII). Abnormal EGFRvIII signaling has been shown to be important in driving tumor… read more here.
Keywords: proliferation glioma; cep55; u251 cells; proliferation ... See more keywords
Expression, association with clinicopathological features and prognostic potential of CEP55, p-Akt, FoxM1 and MMP-2 in astrocytoma
Sign Up to like & getrecommendations! Published in 2020 at "Oncology Letters"
DOI: 10.3892/ol.2020.11742
Abstract: Centrosomal protein 55 (CEP55) is a member of the centrosomal-associated protein family and participates in the regulation of cytokinesis during cell mitosis. However, aberrant CEP55 protein expression has been observed in human tumors. In addition,… read more here.
Keywords: foxm1 mmp; cep55; akt foxm1;
CEP55 as a prognostic indicator and a predictive marker in oral squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Medical Sciences"
DOI: 10.7150/ijms.107996
Abstract: Objective: To investigate the role of CEP55 in the occurrence and development of oral squamous cell carcinoma (OSCC). Materials and Methods: Through the utilization of the online OSCC database and bioinformatic analysis, we examine CEP55… read more here.
Keywords: oral squamous; cell; squamous cell; infiltration ... See more keywords