Modern Template Design and Biological Evaluation of Cephradine-loaded Magnesium Calcium Silicate Nanocomposites as an Inhibitor for Nosocomial Bacteria in Biomedical Applications
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DOI: 10.1007/s12633-020-00642-8
Abstract: Magnesium calcium silicate nanostructures (MCSNS) loaded with (0.0, 0.6, 0.9, and 1.2 wt%) of Cephradine-drug consisting of mesoporous particles were functionally prepared by sol-gel method and treated at 60oC. Bio-functionally nanostructures were characterized by XRD,… read more here.
Keywords: cephradine; silicate; calcium silicate; magnesium calcium ... See more keywords
Computational redesign of penicillin acylase for cephradine synthesis with high kinetic selectivity
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DOI: 10.1039/c8gc03420f
Abstract: Computational redesign of native enzyme active sites for non-natural substrates offers a general approach for creating biocatalysts in green chemistry. Herein, a computational strategy was developed to discover selective mutants of penicillin acylase to catalyze… read more here.
Keywords: penicillin acylase; chemistry; cephradine; computational redesign ... See more keywords