Golgi-Localized PAQR4 Mediates Antiapoptotic Ceramidase Activity in Breast Cancer
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DOI: 10.1158/0008-5472.can-19-3177
Abstract: Induction of and cellular dependency on de novo sphingolipid synthesis via PAQR4 highlights a central vulnerability in breast cancer that may serve as a viable therapeutic target. The metabolic network of sphingolipids plays important roles… read more here.
Keywords: golgi localized; breast cancer; cancer; ceramidase activity ... See more keywords