Autophagy augmentation alleviates cigarette smoke‐induced CFTR‐dysfunction, ceramide‐accumulation and COPD‐emphysema pathogenesis
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DOI: 10.1016/j.freeradbiomed.2018.11.023
Abstract: ABSTRACT In this study, we aimed to investigate precise mechanism(s) of sphingolipid‐imbalance and resulting ceramide‐accumulation in COPD‐emphysema. Where, human and murine emphysema lung tissues or human bronchial epithelial cells (Beas2b) were used for experimental analysis.… read more here.
Keywords: accumulation; ceramide accumulation; copd emphysema; emphysema pathogenesis ... See more keywords
Study on ceramide modulates EAAT-2 participation in the immunoinflammatory response in schizophrenia.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201903_17275
Abstract: OBJECTIVE Abnormal immunoinflammatory responses play important roles in the pathogenesis of schizophrenia, but the underlying molecular mechanisms are still unclear. MATERIALS AND METHODS In this study, the ceramide agonist daunorubicin (DNR) was injected into the… read more here.
Keywords: study ceramide; neuronal damage; schizophrenia; ceramide accumulation ... See more keywords