Ceramide kinase regulates the migration of bone marrow-derived mesenchymal stem cells.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.11.154
Abstract: Endogenous bone marrow-derived mesenchymal stem cells (BM-MSCs) are mobilized into peripheral blood and injured tissues by various growth factors and cytokines that are expressed in the injured tissues, such as substance P (SP), stromal cell… read more here.
Keywords: ceramide kinase; migration; tgf; stem ... See more keywords
Ceramide kinase knockout ameliorates multiple sclerosis-like behaviors and demyelination in cuprizone-treated mice.
Sign Up to like & getrecommendations! Published in 2022 at "Life sciences"
DOI: 10.1016/j.lfs.2022.120446
Abstract: Changes in sphingolipid metabolism regulate and/or alter many cellular functions in the brain. Ceramide, a central molecule of sphingolipid metabolism, is phosphorylated to ceramide-1-phosphate (C1P) by ceramide kinase (CerK). CerK and C1P were reported to… read more here.
Keywords: ceramide kinase; brain; cerk; loss ... See more keywords
Ceramide kinase‐like protein promotes cutaneous squamous cell carcinoma
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DOI: 10.1111/bjd.20442
Abstract: Linked Article: Meyer et al. Br J Dermatol 2021; 185:147–152 . read more here.
Keywords: kinase like; like protein; ceramide kinase; promotes cutaneous ... See more keywords
Decreased Innate Migration of Pro-Inflammatory M1 Macrophages through the Mesothelial Membrane Is Affected by Ceramide Kinase and Ceramide 1-P
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232415977
Abstract: The retrograde flow of endometrial tissues deposited into the peritoneal cavity occurs in women during menstruation. Classically (M1) or alternatively (M2) activated macrophages partake in the removal of regurgitated menstrual tissue. The failure of macrophage… read more here.
Keywords: ceramide kinase; pro inflammatory; migration; membrane ... See more keywords
Characterization of Ceramide Kinase from Basolateral Membranes of Kidney Proximal Tubules: Kinetics, Physicochemical Requirements, and Physiological Relevance
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DOI: 10.3390/ijms262110373
Abstract: Ceramide kinase (CerK) catalyzes the phosphorylation of ceramide to ceramide-1-phosphate (C1P), a bioactive sphingolipid with diverse signaling roles. While CerK has been identified in several cellular compartments, its presence and functional significance in kidney proximal… read more here.
Keywords: kidney proximal; ceramide; ceramide kinase; proximal tubules ... See more keywords