Ceramide Synthases Are Attractive Drug Targets for Treating Metabolic Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2020.00483
Abstract: Ceramide synthases (CerS) are central enzymes required for the de-novo synthesis of ceramides and other sphingolipids. They catalyze the addition of different acyl-chains to a sphingoid base, and thus account for much of the rich… read more here.
Keywords: drug targets; treating metabolic; ceramide synthases; synthases attractive ... See more keywords
The Two Classes of Ceramide Synthases Play Different Roles in Plant Immunity and Cell Death
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.824585
Abstract: Ceramide synthases (CSs) produce ceramides from long-chain bases (LCBs). However, how CSs regulate immunity and cell death in Arabidopsis thaliana remains unclear. Here, we decipher the roles of two classes of CS, CSI (LAG1 HOMOLOG… read more here.
Keywords: cell death; two classes; immunity cell; death ... See more keywords