Convergent evolution of bacterial ceramide synthesis
Sign Up to like & getrecommendations! Published in 2021 at "Nature Chemical Biology"
DOI: 10.1038/s41589-021-00948-7
Abstract: The bacterial domain produces numerous types of sphingolipids with various physiological functions. In the human microbiome, commensal and pathogenic bacteria use these lipids to modulate the host inflammatory system. Despite their growing importance, their biosynthetic… read more here.
Keywords: convergent evolution; ceramide; bacterial ceramide; pathway ... See more keywords
Increased de novo ceramide synthesis and accumulation in failing myocardium.
Sign Up to like & getrecommendations! Published in 2017 at "JCI insight"
DOI: 10.1172/jci.insight.96203
Abstract: Abnormal lipid metabolism may contribute to myocardial injury and remodeling. To determine whether accumulation of very long-chain ceramides occurs in human failing myocardium, we analyzed myocardial tissue and serum from patients with severe heart failure… read more here.
Keywords: novo ceramide; accumulation; ceramide synthesis; failing myocardium ... See more keywords