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   Articles with "cerebellar ataxias" as a keyword



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Impulsivity in Cerebellar Ataxias: Testing the Cerebellar Reward Hypothesis in Humans

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recommendations! Published in 2020 at "Movement Disorders"

DOI: 10.1002/mds.28121

Abstract: were not evaluated by a comprehensive neuropsychological battery. Finally, the results may have been influenced by survival bias. MPS in this population-based sample could be influenced by other factors apart from white-matter changes or small-vessel… read more here.

Keywords: cerebellar ataxias; ataxias testing; testing cerebellar; reward hypothesis ... See more keywords
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Developing a smartphone application, triaxial accelerometer-based, to quantify static and dynamic balance deficits in patients with cerebellar ataxias

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recommendations! Published in 2019 at "Journal of Neurology"

DOI: 10.1007/s00415-019-09570-z

Abstract: Background Cerebellar ataxia is characterized by difficulty in the planning of movement and lack of anticipatory postural adjustments, which can result in deficits of balance. Being able to have quantitative measurements in clinical practice, to… read more here.

Keywords: cerebellar ataxias; dynamic balance; patients cerebellar; static dynamic ... See more keywords
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Pathogenic Roles of Glutamic Acid Decarboxylase 65 Autoantibodies in Cerebellar Ataxias

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recommendations! Published in 2017 at "Journal of Immunology Research"

DOI: 10.1155/2017/2913297

Abstract: Reports suggesting a pathogenic role of autoantibodies directed against glutamic acid decarboxylase 65 (GAD65Abs) in cerebellar ataxias (CAs) are reviewed, and debatable issues such as internalization of antibodies by neurons and roles of epitopes are… read more here.

Keywords: cerebellar ataxias; glutamic acid; pathogenic roles; gad65ab ... See more keywords
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Rehabilitation in patients with cerebellar ataxias.

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recommendations! Published in 2022 at "Arquivos de neuro-psiquiatria"

DOI: 10.1590/0004-282x-anp-2021-0065

Abstract: Cerebellar ataxias comprise a heterogeneous group of diseases characterized by motor and non-motor symptoms, which can be acquired, degenerative, or have a genetic cause, such as spinocerebellar ataxias (SCA). Usually, the genetic and neurodegenerative forms… read more here.

Keywords: patients cerebellar; rehabilitation; therapy; rehabilitation patients ... See more keywords
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Immune-mediated Cerebellar Ataxias: Practical Guidelines and Therapeutic Challenges

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recommendations! Published in 2019 at "Current Neuropharmacology"

DOI: 10.2174/1570159x16666180917105033

Abstract: Immune-mediated cerebellar ataxias (IMCAs), a clinical entity reported for the first time in the 1980s, include gluten ataxia (GA), paraneoplastic cerebellar degenerations (PCDs), anti-glutamate decarboxylase 65 (GAD) antibody-associated cerebellar ataxia, post-infectious cerebellitis, and opsoclonus myoclonus… read more here.

Keywords: practical guidelines; ataxias practical; immune mediated; guidelines therapeutic ... See more keywords

Application of a Clinical Workflow May Lead to Increased Diagnostic Precision in Hereditary Spastic Paraplegias and Cerebellar Ataxias: A Single Center Experience

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recommendations! Published in 2021 at "Brain Sciences"

DOI: 10.3390/brainsci11020246

Abstract: The molecular characterization of Hereditary Spastic Paraplegias (HSP) and inherited cerebellar ataxias (CA) is challenged by their clinical and molecular heterogeneity. The recent application of Next Generation Sequencing (NGS) technologies is increasing the diagnostic rate,… read more here.

Keywords: cerebellar ataxias; hereditary spastic; hsp; center ... See more keywords
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Rare Etiologies in Immune-Mediated Cerebellar Ataxias: Diagnostic Challenges

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recommendations! Published in 2022 at "Brain Sciences"

DOI: 10.3390/brainsci12091165

Abstract: The cerebellum is particularly enriched in antigens and represents a vulnerable target to immune attacks. Immune-mediated cerebellar ataxias (IMCAs) have diverse etiologies, such as gluten ataxia (GA), post-infectious cerebellitis (PIC), Miller Fisher syndrome (MFS), paraneoplastic… read more here.

Keywords: mediated cerebellar; rare etiologies; immune mediated; ataxias diagnostic ... See more keywords
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Fundamental Mechanisms of Autoantibody-Induced Impairments on Ion Channels and Synapses in Immune-Mediated Cerebellar Ataxias

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recommendations! Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms21144936

Abstract: In the last years, different kinds of limbic encephalitis associated with autoantibodies against ion channels and synaptic receptors have been described. Many studies have demonstrated that such autoantibodies induce channel or receptor dysfunction. The same… read more here.

Keywords: cerebellar ataxias; ion channels; mediated cerebellar; immune mediated ... See more keywords