Maternal marginal iodine deficiency limits dendritic growth of cerebellar purkinje cells in rat offspring by NF‐κB signaling and MAP1B
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Toxicology"
DOI: 10.1002/tox.22320
Abstract: Iodine deficiency (ID) during early pregnancy had an adverse effect on children's psychomotor and motor function. It is worth noting that maternal marginal ID tends to be a common public health problem. Whether marginal ID… read more here.
Keywords: maternal marginal; dendritic growth; iodine deficiency; cerebellar purkinje ... See more keywords
Myocyte Enhancer Factor 2c Regulates Dendritic Complexity and Connectivity of Cerebellar Purkinje Cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1363-7
Abstract: Mef2c haploinsufficiency is implicated in behavioral deficits related to autism, schizophrenia, and intellectual disability. Although perturbations in the cerebellum, notably Purkinje cells, have been linked to these neurological disorders, the underlying mechanisms remain poorly understood.… read more here.
Keywords: mef2c expression; purkinje cells; mef2c; cerebellar purkinje ... See more keywords
Intrinsic memory of temporal intervals in cerebellar Purkinje cells
Sign Up to like & getrecommendations! Published in 2019 at "Neurobiology of Learning and Memory"
DOI: 10.1016/j.nlm.2019.107103
Abstract: The general consensus for learning and memory, including in the cerebellum, is that modification of synaptic strength via long-term potentiation (LTP) or long-term depression (LTD) are the primary mechanisms for the formation of memories. Recent… read more here.
Keywords: purkinje; purkinje cell; synaptic strength; cerebellar purkinje ... See more keywords
Distribution of cortactin in cerebellar Purkinje cell spines
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-80469-w
Abstract: Dendritic spines are the primary sites of excitatory transmission in the mammalian brain. Spines of cerebellar Purkinje Cells (PCs) are plastic, but they differ from forebrain spines in a number of important respects, and the… read more here.
Keywords: distribution cortactin; cortactin cerebellar; distribution; cerebellar purkinje ... See more keywords
Maturation of GABAergic Transmission in Cerebellar Purkinje Cells Is Sex Dependent and Altered in the Valproate Model of Autism
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2018.00232
Abstract: Brain development is accompanied by a shift in gamma-aminobutyric acid (GABA) response from depolarizing-excitatory to hyperpolarizing-inhibitory, due to a reduction of intracellular chloride concentration. This sequence is delayed in Autism Spectrum Disorders (ASD). We now… read more here.
Keywords: shift; autism; sex dependent; cerebellar purkinje ... See more keywords
A computational passage-of-time model of the cerebellar Purkinje cell in eyeblink conditioning
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Computational Neuroscience"
DOI: 10.3389/fncom.2023.1108346
Abstract: The cerebellar Purkinje cell controlling eyeblinks can learn, remember, and reproduce the interstimulus interval in a classical conditioning paradigm. Given temporally separated inputs, the cerebellar Purkinje cell learns to pause its tonic inhibition of a… read more here.
Keywords: cell; passage time; purkinje cell; cerebellar purkinje ... See more keywords