Stretch-Induced Intimal Failure in Isolated Cerebral Arteries as a Function of Development.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of biomedical engineering"
DOI: 10.1007/s10439-021-02869-x
Abstract: Recent clinical studies have shown that traumatic brain injury is a significant risk factor for stroke. Motivated to better understand possible mechanisms of this association, we studied subfailure disruption of the intima in overstretched sheep… read more here.
Keywords: cerebral arteries; stretch; disruption; intimal disruption ... See more keywords
Proteomic Expression Changes in Large Cerebral Arteries After Experimental Subarachnoid Hemorrhage in Rat Are Regulated by the MEK-ERK1/2 Pathway
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-017-0944-7
Abstract: Subarachnoid hemorrhage (SAH) is a serious clinical condition where leakage of blood into the subarachnoid space causes an acute rise in intracranial pressure and reduces cerebral blood flow, which may lead to delayed cerebral ischemia… read more here.
Keywords: mek erk1; cerebral arteries; erk1 pathway; subarachnoid hemorrhage ... See more keywords
Vascular pathology of large cerebral arteries in experimental subarachnoid hemorrhage: Vasoconstriction, functional CGRP depletion and maintained CGRP sensitivity
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2019.01.007
Abstract: &NA; Subarachnoid hemorrhage (SAH) is associated with increased cerebral artery sensitivity to vasoconstrictors and release of the perivascular sensory vasodilator CGRP. In the current study the constrictive phenotype and the vasodilatory effects of exogenous and… read more here.
Keywords: cerebral arteries; cgrp; pathology; sensitivity ... See more keywords
Age dependence of critical pressure in the segments and branches of the circle of Willis.
Sign Up to like & getrecommendations! Published in 2017 at "Neurologia i neurochirurgia polska"
DOI: 10.1016/j.pjnns.2017.01.003
Abstract: Spontaneous intracranial haemorrhage is one of the most dramatic neurological disasters. The source of haemorrhage is linked to the pathology of the arterial wall or is unknown. Because the risk of haemorrhagic stroke increases with… read more here.
Keywords: circle willis; cerebral arteries; age; rupture pressure ... See more keywords
Cerebral Aneurysms: Are They Associated with Anatomic Variations of Carotid and Main Cerebral Arteries?
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.12.161
Abstract: OBJECTIVE Vascular anatomic variations are very common in the population, but their coexistence with life-threating vascular malformations remains unclear. The objective of the study was to assess the correlation between the presence of anatomic variants… read more here.
Keywords: cerebral arteries; anatomic variations; cerebral aneurysms; artery ... See more keywords
Development of a globally optimised model of the cerebral arteries.
Sign Up to like & getrecommendations! Published in 2019 at "Physics in medicine and biology"
DOI: 10.1088/1361-6560/ab2479
Abstract: The cerebral arteries are difficult to reproduce from first principles, featuring interwoven territories, and intricate layers of grey and white matter with differing metabolic demand. The aim of this study was to identify the ideal… read more here.
Keywords: cerebral arteries; model cerebral; optimised model; globally optimised ... See more keywords
Traumatic Brain Injury Impairs Myogenic Constriction of Cerebral Arteries: Role of Mitochondria-Derived H2O2 and TRPV4-Dependent Activation of BKca Channels.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of neurotrauma"
DOI: 10.1089/neu.2017.5056
Abstract: Traumatic brain injury (TBI) impairs autoregulation of cerebral blood flow, which contributes to the development of secondary brain injury, increasing mortality of patients. Impairment of pressure-induced myogenic constriction of cerebral arteries plays a critical role… read more here.
Keywords: cerebral arteries; constriction; trpv4; brain injury ... See more keywords
Death-associated protein kinase 3 regulates the myogenic reactivity of cerebral arteries.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental physiology"
DOI: 10.1113/ep090631
Abstract: NEW FINDINGS What is the central question of this study? DAPK3 contributes to the Ca2+ -sensitization of vascular smooth muscle contraction: does this protein kinase participate in the myogenic response of cerebral arteries? What is… read more here.
Keywords: protein kinase; myogenic reactivity; myogenic response; kinase ... See more keywords
Comparison of TOF-MRA and silent scan-MRA in depicting cerebral arteries in patients with Moyamoya disease
Sign Up to like & getrecommendations! Published in 2019 at "Acta Radiologica"
DOI: 10.1177/0284185118824782
Abstract: Background Silent scan magnetic resonance angiography (silent-MRA) as an arterial spin labeling technique offering sound reduction is insensitive to saturation effect. Time-of-flight (TOF)-MRA has limitations in terms of fine or slow-flow blood vessels due to… read more here.
Keywords: cerebral arteries; silent mra; silent scan; mra ... See more keywords
Gender, hyperandrogenism and vitamin D deficiency related functional and morphological alterations of rat cerebral arteries
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DOI: 10.1371/journal.pone.0216951
Abstract: Hyperandrogenism is a risk factor of cerebrovascular diseases as androgens can alter markedly the regulation of cerebrovascular tone. We examined the combined impact of androgen excess and vitamin D deficiency (VDD), a common co-morbidity in… read more here.
Keywords: cerebral arteries; androgen; hyperandrogenism; testosterone induced ... See more keywords
The effect of intensive statin therapy in non-symptomatic intracranial arteries: The STAMINA-MRI sub-study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2023.1069502
Abstract: Background and aims Pleiotropic effects of statins result in the stabilization of symptomatic intracranial arterial plaque. However, little is known about the effect of statins in non-symptomatic cerebral arteries. We hypothesized that intensive statin therapy… read more here.
Keywords: non symptomatic; cerebral arteries; statin therapy; intensive statin ... See more keywords