Articles with "cerebral cortex" as a keyword



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Association between carotid atheroma and cerebral cortex structure at age 73 years

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Published in 2018 at "Annals of Neurology"

DOI: 10.1002/ana.25324

Abstract: To examine the relationship between carotid atherosclerosis and cerebral cortical thickness and investigate whether cortical thickness mediates the association between carotid atheroma and relative cognitive decline. read more here.

Keywords: cerebral cortex; association carotid; atheroma cerebral; cortex structure ... See more keywords

E3 ubiquitin ligases and cerebral cortex development in health and disease

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Published in 2022 at "Developmental Neurobiology"

DOI: 10.1002/dneu.22877

Abstract: Cerebral cortex development involves the sequential progression of biological steps driven by molecular pathways whose tight regulation often relies on ubiquitination. Ubiquitination is a posttranslational modification involved in all aspects of cellular homeostasis through the… read more here.

Keywords: cerebral cortex; development; ligases cerebral; ubiquitin ligases ... See more keywords

Evolutionary innovations of human cerebral cortex viewed through the lens of high‐throughput sequencing

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Published in 2022 at "Developmental Neurobiology"

DOI: 10.1002/dneu.22893

Abstract: Humans had acquired a tremendously enlarged cerebral cortex containing a huge quantity and variety of cells during evolution. Such evolutionary uniqueness offers a neural basis of our cognitive innovation and human‐specific features of neurodevelopmental and… read more here.

Keywords: evolutionary innovations; cerebral cortex; high throughput; cortex ... See more keywords

Quercetin attenuates cyclophosphamide induced‐immunosuppressive indoleamine 2,3‐dioxygenase in the hippocampus and cerebral cortex of male Wister rats

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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23179

Abstract: This study investigated the protective effect of quercetin against cyclophosphamide‐induced immunosuppressive indoleamine 2,3‐dioxygenase (IDO) via the mechanism of oxidative‐inflammatory stress and behavioral indices. Cyclophosphamide (CYP) was administered to male Wister rats at a dose of… read more here.

Keywords: cerebral cortex; wister rats; male wister; dioxygenase ... See more keywords

Daidzein Attenuates Cadmium‐Induced Neurotoxicity via Inhibiting Apoptosis and Mitophagy in the Cerebral Cortex of Sprague–Dawley Rats

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Published in 2025 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.70299

Abstract: Cadmium (Cd), a prevalent environmental pollutant, is of significant concern owing to its neurotoxicity; thus, the identification of effective interventions for nerve injury caused by Cd is crucial. Mitochondrial signaling pathway‐mediated apoptosis and PTEN‐induced putative… read more here.

Keywords: sprague dawley; cerebral cortex; induced neurotoxicity; apoptosis ... See more keywords

Histopathological Alterations and Dysregulation of Type I Interferon Signaling in the Human Cerebral Cortex During Severe Dengue

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Published in 2025 at "Journal of Medical Virology"

DOI: 10.1002/jmv.70644

Abstract: Dengue virus (DENV) is a major arthropod‐borne pathogen, endemic in over 100 countries and posing global health challenges. While innate immune responses and viral evasion mechanisms have been extensively studied in animal models and mononuclear… read more here.

Keywords: histopathological alterations; dengue; severe dengue; cerebral cortex ... See more keywords

Mapping the community structure of the rat cerebral cortex with weighted stochastic block modeling

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Published in 2019 at "Brain Structure and Function"

DOI: 10.1007/s00429-019-01984-9

Abstract: The anatomical architecture of the mammalian brain can be modeled as the connectivity between functionally distinct areas of cortex and sub-cortex, which we refer to as the connectome . The community structure of the connectome… read more here.

Keywords: cortex; cerebral cortex; community; community structure ... See more keywords

Integrated lipidomic and transcriptomic analysis reveals clarithromycin-induced alteration of glycerophospholipid metabolism in the cerebral cortex of mice.

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Published in 2021 at "Cell biology and toxicology"

DOI: 10.1007/s10565-021-09646-5

Abstract: Clarithromycin (CLA) has been widely used in the treatment of bacterial infection. Research reveals the adverse effects on the central nervous system among patients receiving CLA treatment; whereas, a relevant underlying mechanism remains considerably unclear.… read more here.

Keywords: metabolism; cerebral cortex; cla; integrated lipidomic ... See more keywords

Acute administration of methionine and/or methionine sulfoxide impairs redox status and induces apoptosis in rat cerebral cortex

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Published in 2017 at "Metabolic Brain Disease"

DOI: 10.1007/s11011-017-0054-9

Abstract: High plasma levels of methionine (Met) and its metabolites such as methionine sulfoxide (MetO) may occur in several genetic abnormalities. Patients with hypermethioninemia can present neurological dysfunction; however, the neurotoxicity mechanisms induced by these amino… read more here.

Keywords: cerebral cortex; meto; meto met; met meto ... See more keywords

Neutrophil Infiltration and Matrix Metalloproteinase-9 in Lacunar Infarction

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Published in 2017 at "Neurochemical Research"

DOI: 10.1007/s11064-017-2265-1

Abstract: We use the modified pial vessel disruption rat model to elucidate the cellular and molecular mechanisms of cavitation as it plays a role in lacunar infarction. Here we discuss the similarities between the genesis of… read more here.

Keywords: cerebral cortex; matrix metalloproteinase; cavitation; lacunar infarction ... See more keywords

The effect of iron nanoparticles on performance of cognitive tasks in rats

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Published in 2017 at "Environmental Science and Pollution Research"

DOI: 10.1007/s11356-017-8531-6

Abstract: To assess the influence of 62.5 ± 0.6 nm iron nanoparticles on the status of central nervous system, a study was conducted on Wistar rats, which were subjected to abdominal injection of the studied nanoparticles at doses of… read more here.

Keywords: cerebral cortex; iron nanoparticles; effect iron; nanoparticles performance ... See more keywords