Association between carotid atheroma and cerebral cortex structure at age 73 years
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Neurology"
DOI: 10.1002/ana.25324
Abstract: To examine the relationship between carotid atherosclerosis and cerebral cortical thickness and investigate whether cortical thickness mediates the association between carotid atheroma and relative cognitive decline. read more here.
Keywords: cerebral cortex; association carotid; atheroma cerebral; cortex structure ... See more keywords
E3 ubiquitin ligases and cerebral cortex development in health and disease
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22877
Abstract: Cerebral cortex development involves the sequential progression of biological steps driven by molecular pathways whose tight regulation often relies on ubiquitination. Ubiquitination is a posttranslational modification involved in all aspects of cellular homeostasis through the… read more here.
Keywords: cerebral cortex; development; ligases cerebral; ubiquitin ligases ... See more keywords
Evolutionary innovations of human cerebral cortex viewed through the lens of high‐throughput sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22893
Abstract: Humans had acquired a tremendously enlarged cerebral cortex containing a huge quantity and variety of cells during evolution. Such evolutionary uniqueness offers a neural basis of our cognitive innovation and human‐specific features of neurodevelopmental and… read more here.
Keywords: evolutionary innovations; cerebral cortex; high throughput; cortex ... See more keywords
Quercetin attenuates cyclophosphamide induced‐immunosuppressive indoleamine 2,3‐dioxygenase in the hippocampus and cerebral cortex of male Wister rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23179
Abstract: This study investigated the protective effect of quercetin against cyclophosphamide‐induced immunosuppressive indoleamine 2,3‐dioxygenase (IDO) via the mechanism of oxidative‐inflammatory stress and behavioral indices. Cyclophosphamide (CYP) was administered to male Wister rats at a dose of… read more here.
Keywords: cerebral cortex; wister rats; male wister; dioxygenase ... See more keywords
Mapping the community structure of the rat cerebral cortex with weighted stochastic block modeling
Sign Up to like & getrecommendations! Published in 2019 at "Brain Structure and Function"
DOI: 10.1007/s00429-019-01984-9
Abstract: The anatomical architecture of the mammalian brain can be modeled as the connectivity between functionally distinct areas of cortex and sub-cortex, which we refer to as the connectome . The community structure of the connectome… read more here.
Keywords: cortex; cerebral cortex; community; community structure ... See more keywords
Integrated lipidomic and transcriptomic analysis reveals clarithromycin-induced alteration of glycerophospholipid metabolism in the cerebral cortex of mice.
Sign Up to like & getrecommendations! Published in 2021 at "Cell biology and toxicology"
DOI: 10.1007/s10565-021-09646-5
Abstract: Clarithromycin (CLA) has been widely used in the treatment of bacterial infection. Research reveals the adverse effects on the central nervous system among patients receiving CLA treatment; whereas, a relevant underlying mechanism remains considerably unclear.… read more here.
Keywords: metabolism; cerebral cortex; cla; integrated lipidomic ... See more keywords
Acute administration of methionine and/or methionine sulfoxide impairs redox status and induces apoptosis in rat cerebral cortex
Sign Up to like & getrecommendations! Published in 2017 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-017-0054-9
Abstract: High plasma levels of methionine (Met) and its metabolites such as methionine sulfoxide (MetO) may occur in several genetic abnormalities. Patients with hypermethioninemia can present neurological dysfunction; however, the neurotoxicity mechanisms induced by these amino… read more here.
Keywords: cerebral cortex; meto; meto met; met meto ... See more keywords
Neutrophil Infiltration and Matrix Metalloproteinase-9 in Lacunar Infarction
Sign Up to like & getrecommendations! Published in 2017 at "Neurochemical Research"
DOI: 10.1007/s11064-017-2265-1
Abstract: We use the modified pial vessel disruption rat model to elucidate the cellular and molecular mechanisms of cavitation as it plays a role in lacunar infarction. Here we discuss the similarities between the genesis of… read more here.
Keywords: cerebral cortex; matrix metalloproteinase; cavitation; lacunar infarction ... See more keywords
The effect of iron nanoparticles on performance of cognitive tasks in rats
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-017-8531-6
Abstract: To assess the influence of 62.5 ± 0.6 nm iron nanoparticles on the status of central nervous system, a study was conducted on Wistar rats, which were subjected to abdominal injection of the studied nanoparticles at doses of… read more here.
Keywords: cerebral cortex; iron nanoparticles; effect iron; nanoparticles performance ... See more keywords
Potential Protective Effect of Riboflavin Against Pathological Changes in the Main Organs of Male Mice Induced by Fluoride Exposure.
Sign Up to like & getrecommendations! Published in 2021 at "Biological trace element research"
DOI: 10.1007/s12011-021-02746-7
Abstract: Long-term exposure to excessive fluorine could cause damage to various tissues and organs in human and animals. However, there is no effective antidote to prevent and cure fluorosis except for avoiding fluoride intake. As an… read more here.
Keywords: pathological changes; cerebral cortex; exposure; male mice ... See more keywords
Chronic Cerebral Hypoperfusion Induced Synaptic Proteome Changes in the rat Cerebral Cortex
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0641-0
Abstract: Chronic cerebral hypoperfusion (CCH) evokes mild cognitive impairment (MCI) and contributes to the progression of vascular dementia and Alzheimer’s disease (AD). How CCH induces these neurodegenerative processes that may spread along the synaptic network and… read more here.
Keywords: protein; cerebral hypoperfusion; cerebral cortex; cch ... See more keywords