Association of Modifiable Lifestyle Factors With Cortical Amyloid Burden and Cerebral Glucose Metabolism in Older Adults With Mild Cognitive Impairment
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.5719
Abstract: Key Points Question Are modifiable lifestyle factors associated with cortical amyloid burden or cerebral glucose metabolism in older adults with mild cognitive impairment? Findings This cohort study included 118 older adults with mild cognitive impairment… read more here.
Keywords: adults mild; cognitive impairment; impairment; cerebral glucose ... See more keywords
Simultaneous assessment of cerebral glucose and oxygen metabolism and perfusion in rats using interleaved deuterium (2H) and oxygen‐17 (17O) MRS
Sign Up to like & getrecommendations! Published in 2024 at "Nmr in Biomedicine"
DOI: 10.1002/nbm.5284
Abstract: Cerebral glucose and oxygen metabolism and blood perfusion play key roles in neuroenergetics and oxidative phosphorylation to produce adenosine triphosphate (ATP) energy molecules in supporting cellular activity and brain function. Their impairments have been linked… read more here.
Keywords: cerebral glucose; oxygen; metabolism; perfusion ... See more keywords
Association of vascular endothelial growth factor levels in CSF and cerebral glucose metabolism across the Alzheimer’s disease spectrum
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.09.055
Abstract: The association of vascular endothelial growth factor (VEGF) levels in CSF and cerebral glucose metabolism across the Alzheimer's disease (AD) spectrum is unclear. CSF VEGF levels were cross-sectionally related to cerebral glucose metabolism, as measured… read more here.
Keywords: vascular endothelial; endothelial growth; glucose metabolism; cerebral glucose ... See more keywords
Associations of cigarette smoking with memory decline and neurodegeneration among cognitively normal older individuals
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.134563
Abstract: Cigarette smoking is associated with a higher risk of Alzheimer's disease (AD), but the underlying mechanisms remain to be clarified. In this study, we aimed to examine the effects of cigarette smoking on multiple AD… read more here.
Keywords: non smokers; cigarette smoking; smokers smokers; cerebral glucose ... See more keywords
Non-invasive quantification of cerebral glucose metabolism using Gjedde-Patlak plot and image-derived input function from the aorta
Sign Up to like & getrecommendations! Published in 2022 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2022.119079
Abstract: INTRODUCTION We aimed at evaluating a Gjedde-Patlak plot and non-invasive image-derived input functions (IDIF) from the aorta to quantify cerebral glucose metabolic rate (CMRglc) in comparison to the reference standard based on sampling the arterial… read more here.
Keywords: plot; function; cerebral glucose; gjedde patlak ... See more keywords
Variability of clinical syndromes and cerebral glucose metabolism in symptomatic frontotemporal lobar degeneration associated with progranulin mutations
Sign Up to like & getrecommendations! Published in 2020 at "Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"
DOI: 10.1080/21678421.2020.1779302
Abstract: Abstract Objective: The aims of our study were to describe the clinical phenotype and to characterize the cerebral glucose metabolism patterns as measured with fluordesoxyglucose-positron emission tomography (FDG-PET) in symptomatic FTLD-patients with different GRN variants.… read more here.
Keywords: glucose metabolism; clinical syndromes; variability clinical; cerebral glucose ... See more keywords
Abstract TP215: Impact of Carotid Stenosis on Cerebral Glucose Metabolism
Sign Up to like & getrecommendations! Published in 2025 at "Stroke"
DOI: 10.1161/str.56.suppl_1.tp215
Abstract: Background: Carotid stenosis has been associated with stroke and cognitive impairment. It remains unclear if hypometablism, a marker for neurodegeneration, may be in the mechanistic pathway in the association between carotid stenosis and cognitive decline.… read more here.
Keywords: cerebral glucose; stenosis; carotid stenosis; glucose metabolism ... See more keywords
CSF Amyloid-β42 associates with neuropsychiatric and cognitive outcomes via cerebral glucose metabolism
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Brain"
DOI: 10.1186/s13041-025-01229-3
Abstract: Amyloid-β42 (Aβ42) regulates synaptic plasticity and memory formation at physiological levels in the brain, but in Alzheimer’s disease (AD), it can disrupt brain function and glucose metabolism. This disruption contributes to cognitive decline and neuropsychiatric… read more here.
Keywords: cerebral glucose; glucose metabolism; group; metabolism ... See more keywords
Asymmetry of cerebral glucose metabolism in very low-birth-weight infants without structural abnormalities
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0186976
Abstract: Even when structural abnormalities are not observed on the brain magnetic resonance images (MRI) of very low-birth-weight (VLBW) infants, such infants are at increased risk for poor neurodevelopment. The aim of the present study was… read more here.
Keywords: structural abnormalities; asymmetry; glucose metabolism; cerebral glucose ... See more keywords
A Retrospective Case Series Analysis of the Relationship Between Phenylalanine: Tyrosine Ratio and Cerebral Glucose Metabolism in Classical Phenylketonuria and Hyperphenylalaninemia
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2021.664525
Abstract: We retrospectively examined the relationship between blood biomarkers, in particular the historical mean phenylalanine to tyrosine (Phe:Tyr) ratio, and cerebral glucose metabolism. We hypothesized that the historical mean Phe:Tyr ratio would be more predictive of… read more here.
Keywords: tyr ratio; phe; phe tyr; cerebral glucose ... See more keywords
Cerebral glucose changes after chemotherapy and their relation to long-term cognitive complaints and fatigue
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1021615
Abstract: Purpose To investigate the short-term cerebral metabolic effects of intravenous chemotherapy and their association with long-term fatigue/cognitive complaints. Experimental design Using [18F]-FDG-PET/CT whole-body scans, we retrospectively quantified relative cerebral glucose metabolism before and after neoadjuvant… read more here.
Keywords: long term; metabolism; term; complaints fatigue ... See more keywords