Serum Exosomal microRNA-27-3p Aggravates Cerebral Injury and Inflammation in Patients with Acute Cerebral Infarction by Targeting PPARγ
Sign Up to like & getrecommendations! Published in 2021 at "Inflammation"
DOI: 10.1007/s10753-020-01399-3
Abstract: Acute cerebral infarction (ACI) possesses high mortality. Exosomes present in serum have potential application value in ACI diagnosis. This study investigated the mechanism of serum exosomes in ACI. Serum exosomes isolated from ACI patients and… read more here.
Keywords: mir; inflammation; serum; cerebral injury ... See more keywords
Patchouli alcohol protects against ischemia/reperfusion-induced brain injury via inhibiting neuroinflammation in normal and obese mice
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2017.12.039
Abstract: Almost all of the candidate drugs for ischemic stroke failed to be translated from bench to beside. One important reason is that animals used in experimental studies cannot mimic ischemic patients due to lack of… read more here.
Keywords: obese mice; inflammation; cerebral injury; brain ... See more keywords
miR-18b attenuates cerebral ischemia/reperfusion injury through regulation of ANXA3 and PI3K/Akt signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2020.04.021
Abstract: Recent, research has displayed that the disorders of miR-18b are related to ischemic stroke. Here, we aimed to investigate the underlying neuroprotective mechanism of miR-18b in cerebral ischemia/reperfusion (I/R) injury. Oxygen-glucose deprivation/reperfusion (OGDR) model in… read more here.
Keywords: cerebral ischemia; pi3k akt; reperfusion; cerebral injury ... See more keywords
The beneficial roles of metformin on the brain with cerebral ischaemia/reperfusion injury.
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacological research"
DOI: 10.1016/j.phrs.2019.104261
Abstract: Cerebral ischaemia/reperfusion (I/R) injury is the transient loss, followed by rapid return, of blood flow to the brain. This condition is often caused by strokes and heart attacks. The underlying mechanisms resulting in brain damage… read more here.
Keywords: cerebral ischaemia; cerebral injury; brain; ischaemia reperfusion ... See more keywords
MiR-455-5p attenuates cerebral ischemic reperfusion injury via targeting FLT3.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000898
Abstract: Cerebral ischemia-reperfusion (I/R) injury is a terrible disease which results in the dysfunction and structural damage of brain tissues. Growing evidence implies that miR-455-5p is implicated in the regulation of pathogenesis of several diseases. The… read more here.
Keywords: injury via; reperfusion injury; cerebral injury; mir 455 ... See more keywords
KIF2 mediates the neuroprotection in cerebral ischaemia injury by affecting NF‐κB pathway
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13175
Abstract: Stroke is the most common cerebrovascular disease with high morbidity and mortality around the world. However, the underlying mechanisms involved in nerve injury and cerebral ischaemia/reperfusion (I/R) during cerebrovascular disease are still not completely clear.… read more here.
Keywords: cerebral ischaemia; kif2; cerebral injury; injury ... See more keywords
SMAD3 interacts with vitamin D receptor and affects vitamin D‐mediated oxidative stress to ameliorate cerebral ischaemia–reperfusion injury
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.15833
Abstract: Cerebral ischaemia/reperfusion (I/R) injury is caused by blood flow restoration after an ischaemic insult, and effective treatments targeting I/R injury are still insufficient. Oxidative stress plays a critical role in the pathogenesis of cerebral I/R… read more here.
Keywords: cerebral injury; smad3; oxidative stress; cerebral ischaemia ... See more keywords
miR-92b-3p Exerts Neuroprotective Effects on Ischemia/Reperfusion-Induced Cerebral Injury via Targeting NOX4 in a Rat Model
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/3494262
Abstract: The necessity to increase the efficiency of organ preservation has pushed researchers to consider the mechanisms to minimize cerebral ischemia/reperfusion (I/R) injury. Hence, we evaluated the role of the miR-92b-3p/NOX4 pathway in cerebral I/R injury.… read more here.
Keywords: cerebral injury; model; ischemia reperfusion; injury ... See more keywords
Incidence of Cerebral Injury in Monochorionic Twin Survivors after Spontaneous Single Demise: Long-Term Outcome of a Large Cohort
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DOI: 10.1159/000500774
Abstract: Objectives: To evaluate incidence of cerebral injury and outcome in a large series of monochorionic (MC) twin survivors after spontaneous single fetal demise. Methods: Retrospective analysis of all MC pregnancies with single fetal demise diagnosed… read more here.
Keywords: incidence cerebral; cerebral injury; demise; single demise ... See more keywords
Association between Multi-Organ Involvement and Brain Injury in Cooled Newborns: A Statistical Approach
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Neuroscience"
DOI: 10.1159/000523866
Abstract: Introduction: In the event of fetal hypoxia-ischemia, circulation to the brain and central organs is thought to be preserved. The objective of the study was to explore the relationship between the presence of brain injury… read more here.
Keywords: organ involvement; cerebral injury; brain; multi organ ... See more keywords
Seventh Cervical Nerve (C7) Transection for Spastic Arm Paralysis After Cerebral Injury
Sign Up to like & getrecommendations! Published in 2022 at "Operative Neurosurgery"
DOI: 10.1227/ons.0000000000000521
Abstract: BACKGROUND: Spastic limb paralysis because of cerebral injury can cause long-term disability. Its treatment varies from conservative to operative; however, the optimum treatment is yet to be found. OBJECTIVE: To test the hypothesis that patients… read more here.
Keywords: paralysis; spastic arm; arm paralysis; cerebral injury ... See more keywords