Comparative Effectiveness of Diversion of Cerebrospinal Fluid for Children With Severe Traumatic Brain Injury
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.20969
Abstract: Key Points Question Is cerebrospinal fluid (CSF) diversion associated with improved outcomes or intracranial pressure in children with severe traumatic brain injury (TBI)? Findings In this comparative effectiveness study of 1000 children with severe TBI,… read more here.
Keywords: traumatic brain; severe traumatic; cerebrospinal fluid; diversion ... See more keywords
Association of Cerebrospinal Fluid Neurofilament Heavy Protein Levels With Clinical Progression in Patients With Parkinson Disease
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.23821
Abstract: Key Points Question Are cerebrospinal fluid (CSF) neurofilament heavy (cNfH) levels associated with clinical progression in patients with Parkinson disease? Findings In this cohort study of 404 patients with Parkinson disease, higher baseline cNfH levels… read more here.
Keywords: patients parkinson; progression; parkinson disease; cerebrospinal fluid ... See more keywords
Soluble CD27 Levels in Cerebrospinal Fluid as a Prognostic Biomarker in Clinically Isolated Syndrome
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2016.4997
Abstract: Importance There is a growing number of therapies that could be administered after the first symptom of central nervous system demyelination. These drugs can delay multiple sclerosis (MS) diagnosis and slow down future disability. However,… read more here.
Keywords: scd27 levels; patients cis; fluid; relapse rate ... See more keywords
Anti-SARS-CoV-2 and Autoantibody Profiles in the Cerebrospinal Fluid of 3 Teenaged Patients With COVID-19 and Subacute Neuropsychiatric Symptoms.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2021.3821
Abstract: Importance Neuropsychiatric manifestations of COVID-19 have been reported in the pediatric population. Objective To determine whether anti-SARS-CoV-2 and autoreactive antibodies are present in the cerebrospinal fluid (CSF) of pediatric patients with COVID-19 and subacute neuropsychiatric… read more here.
Keywords: neurology; subacute neuropsychiatric; anti sars; patients covid ... See more keywords
Bibrachial Amyotrophy Due to Spontaneous Spinal Cerebrospinal Fluid Leak.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.5388
Abstract: This case report describes a patient with bibrachial amyotrophy due to spontaneous spinal cerebrospinal fluid leak. read more here.
Keywords: bibrachial amyotrophy; spinal cerebrospinal; cerebrospinal fluid; spontaneous spinal ... See more keywords
Systemic Anti–PD-1 Immunotherapy Results in PD-1 Blockade on T Cells in the Cerebrospinal Fluid
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2020.4508
Abstract: This case series evaluates pembrolizumab concentrations and programmed cell death 1 blockade on T cells in cerebrospinal fluid after intravenous administration. read more here.
Keywords: anti immunotherapy; cells cerebrospinal; immunotherapy results; blockade cells ... See more keywords
Prospective detection of mutations in cerebrospinal fluid, pleural effusion, and ascites of advanced cancer patients to guide treatment decisions
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12574
Abstract: Many advanced cases of cancer show central nervous system, pleural, or peritoneal involvement. In this study, we prospectively analyzed if cerebrospinal fluid (CSF), pleural effusion (PE), and/or ascites (ASC) can be used to detect driver… read more here.
Keywords: treatment; guide treatment; pleural effusion; cancer ... See more keywords
Cerebrospinal fluid T1 value phantom reproduction at scan room temperature
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.12659
Abstract: Abstract The T1 value of pure water, which is often used as a phantom to simulate cerebrospinal fluid, is significantly different from that of in‐vivo cerebrospinal fluid. The purpose of this study was to develop… read more here.
Keywords: room temperature; value; cerebrospinal fluid;
Cerebrospinal fluid protein carbonylation identifies oxidative damage in autoimmune demyelination
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.379
Abstract: Oxidative damage occurs in multiple sclerosis, but is difficult to identify antemortem and remains an unknown contributor to disease progression. Carbonylation is a quantitative measure of protein oxidation. Cerebrospinal fluid samples from multiple sclerosis patients… read more here.
Keywords: protein; oxidative damage; carbonylation; cerebrospinal fluid ... See more keywords
Postoperative changes in cognition and cerebrospinal fluid neurodegenerative disease biomarkers
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51499
Abstract: Numerous investigators have theorized that postoperative changes in Alzheimer's disease neuropathology may underlie postoperative neurocognitive disorders. Thus, we determined the relationship between postoperative changes in cognition and cerebrospinal (CSF) tau, p‐tau‐181p, or Aβ levels after… read more here.
Keywords: fluid neurodegenerative; changes cognition; postoperative changes; disease ... See more keywords
Clinical utility of cerebrospinal fluid biomarkers measured by LUMIPULSE® system
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51681
Abstract: Cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) are well‐established in research settings, but their use in routine clinical practice remains a largely unexploited potential. Here, we examined the relationship between CSF biomarkers, measured by… read more here.
Keywords: biomarkers measured; cerebrospinal fluid; clinical utility; utility cerebrospinal ... See more keywords