A novel in vivo Cerenkov luminescence image-guided surgery on primary and metastatic colorectal cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biophotonics"
DOI: 10.1002/jbio.201960152
Abstract: Intraoperative Cerenkov luminescence imaging (CLI) can effectively improve the performance of tumor surgery. Nevertheless, the existing approaches are still unsatisfying to the clinical demands of open surgery. This study develops a novel intraoperative in vivo… read more here.
Keywords: cerenkov luminescence; guided surgery; image guided;
A novel weighted auxiliary set matching pursuit method for glioma in Cerenkov luminescence tomography reconstruction
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202200126
Abstract: Cerenkov luminescence tomography (CLT) is a promising three‐dimensional imaging technology that has been actively investigated in preclinical studies. However, because of the ill‐posedness in the inverse problem of CLT reconstruction, the reconstruction performance is still… read more here.
Keywords: cerenkov luminescence; weighted auxiliary; luminescence tomography; reconstruction ... See more keywords
Quantitative Measurement of the Thyroid Uptake Function of Mouse by Cerenkov Luminescence Imaging
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-05516-5
Abstract: Cerenkov luminescence imaging (CLI) has been an evolutional and alternative approach of nuclear imaging in basic research. This study aimed to measure the 131I thyroid uptake of mouse using CLI for assessment of thyroid function.… read more here.
Keywords: cerenkov luminescence; 131i thyroid; luminescence imaging; uptake function ... See more keywords
In situ excitation of BODIPY fluorophores by 89Zr-generated Cerenkov luminescence.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03875g
Abstract: Secondary Cerenkov-induced fluorescence imaging (SCIFI) is an emerging optical imaging technology that affords high signal-to-noise images by utilising radionuclide-generated Cerenkov luminescence to excite fluorescent probes. BODIPY dyes offer attractive properties for SCIFI, including high quantum… read more here.
Keywords: cerenkov luminescence; generated cerenkov; excitation bodipy; situ excitation ... See more keywords
A novel Cerenkov luminescence tomography approach using multilayer fully connected neural network.
Sign Up to like & getrecommendations! Published in 2019 at "Physics in medicine and biology"
DOI: 10.1088/1361-6560/ab5bb4
Abstract: Cerenkov luminescence tomography (CLT) has been proved as an effective tool for various biomedical applications. Because of the severe scattering of Cerenkov luminescence, the performance of CLT remains unsatisfied. This paper proposed a novel CLT… read more here.
Keywords: cerenkov luminescence; network; clt; approach ... See more keywords
Cerenkov luminescence and PET imaging of 90Y: capabilities and limitations in small animal applications.
Sign Up to like & getrecommendations! Published in 2020 at "Physics in medicine and biology"
DOI: 10.1088/1361-6560/ab7502
Abstract: The in vivo sensitivity limits and quantification performance of Cerenkov luminescence imaging have been studied using a tissue-like mouse phantom and 90Y. For a small, 9 mm deep target in the phantom, with no background… read more here.
Keywords: luminescence pet; cerenkov luminescence; pet imaging; small animal ... See more keywords
A novel denoising framework for cerenkov luminescence imaging based on spatial information improved clustering and curvature-driven diffusion
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Innovative Optical Health Sciences"
DOI: 10.1142/s1793545818500177
Abstract: With widely availed clinically used radionuclides, Cerenkov luminescence imaging (CLI) has become a potential tool in the field of optical molecular imaging. However, the impulse noises introduced ... read more here.
Keywords: novel denoising; cerenkov luminescence; luminescence imaging; framework cerenkov ... See more keywords
Abstract 1869: Improved image-guided surgical resection of glioblastoma with [18F]-fluoroethyltyrosine Cerenkov luminescence imaging
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-1869
Abstract: The ability of a surgeon to completely resect a tumor is directly related to outcome in high- and low-grade gliomas. However current intraoperative navigational tools are useful only in a subset of glioma patients and… read more here.
Keywords: improved image; cerenkov luminescence; luminescence imaging; glioblastoma ... See more keywords
Cerenkov luminescence imaging is an effective preclinical tool for assessing colorectal cancer PD-L1 levels in vivo
Sign Up to like & getrecommendations! Published in 2020 at "EJNMMI Research"
DOI: 10.1186/s13550-020-00654-w
Abstract: Background Preclinical and clinical studies have demonstrated that immunotherapy has effectively delayed tumor progression, and the clinical outcomes of anti-PD-1/PD-L1 therapy were related to PD-L1 expression level in the tumors. A 131 I-labeled anti-PD-L1 monoclonal… read more here.
Keywords: cerenkov luminescence; 131 mab; colorectal cancer; luminescence imaging ... See more keywords
Enhanced Cerenkov luminescence tomography analysis based on Y2O3:Eu3+ rare earth oxide nanoparticles.
Sign Up to like & getrecommendations! Published in 2018 at "Biomedical optics express"
DOI: 10.1364/boe.9.006091
Abstract: Cerenkov luminescence imaging offers a new diagnostic alternative to radiation imaging, but lacks intensity and penetration. In this study, a Cerenkov luminescence signal and its image quality were enhanced using rare earth oxide nanoparticles as… read more here.
Keywords: cerenkov luminescence; earth oxide; rare earth; oxide nanoparticles ... See more keywords