Cerina: systematic circRNA functional annotation based on integrative analysis of ceRNA interactions
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-78469-x
Abstract: Circular RNAs, a family of covalently circularized RNAs with tissue-specific expression, were recently demonstrated to play important roles in mammalian biology. Regardless of extensive research to predict, quantify, and annotate circRNAs, our understanding of their… read more here.
Keywords: cerina systematic; analysis; systematic circrna; cerna interactions ... See more keywords
High-throughput validation of ceRNA regulatory networks
Sign Up to like & getrecommendations! Published in 2017 at "BMC Genomics"
DOI: 10.1186/s12864-017-3790-7
Abstract: BackgroundMicroRNAs (miRNAs) play multiple roles in tumor biology. Interestingly, reports from multiple groups suggest that miRNA targets may be coupled through competitive stoichiometric sequestration. Specifically, computational models predicted and experimental assays confirmed that miRNA activity… read more here.
Keywords: mirna targets; cerna; throughput validation; validation cerna ... See more keywords