Articles with "cerna network" as a keyword



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Construction of circRNA-based ceRNA network and its prognosis-associated subnet of clear cell renal cell carcinoma.

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Published in 2021 at "Cancer medicine"

DOI: 10.1002/cam4.4311

Abstract: Circular RNAs (circRNAs) are novel biomarkers of various cancers. CircRNAs can sponge miRNAs and regulate target mRNAs, which was called competing endogenous RNAs (ceRNA). This study was designed to identify circRNAs related to patients with… read more here.

Keywords: cell renal; renal cell; cell carcinoma; cerna network ... See more keywords
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Identification of a dysregulated ceRNA network modulated by copy number variation‐driven lncRNAs in lung squamous cell carcinoma

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Published in 2022 at "Environmental and Molecular Mutagenesis"

DOI: 10.1002/em.22509

Abstract: Lung cancer is primarily responsive for cancer death, and its progression is aggressively affected by copy number variation (CNV). Through bioinformatics approach, a ceRNA network of CNV‐driven lncRNAs in lung squamous cell carcinoma (LUSC) patients… read more here.

Keywords: cell; cerna network; cnv; lung ... See more keywords
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The exploration of new therapeutic targets for HPV‐negative head and neck squamous cell cancer through the construction of a ceRNA network and immune microenvironment analysis

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Published in 2020 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.29615

Abstract: Previous studies have shown that human papillomavirus (HPV)‐negative patients with head and neck squamous cell cancer (HNSCC) suffer from an unsatisfactory prognosis. Long noncoding RNAs (lncRNAs) have been verified to participate in many biological processes,… read more here.

Keywords: network; analysis; cerna network; immune microenvironment ... See more keywords
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Application of lncRNA–miRNA–mRNA ceRNA network analysis in the treatment of androgenic alopecia

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Published in 2022 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.24791

Abstract: Long noncoding RNAs (lncRNAs) can be used as competitive endogenous RNAs (ceRNAs) to bind to microRNAs (miRNAs) to regulate gene expression. Previous studies have demonstrated that ceRNAs play an important role in the development of… read more here.

Keywords: androgenic alopecia; mirna mrna; cerna network; lncrna mirna ... See more keywords
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Analyzing the interactions of mRNAs, miRNAs, lncRNAs and circRNAs to predict competing endogenous RNA networks in glioblastoma

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Published in 2018 at "Journal of Neuro-Oncology"

DOI: 10.1007/s11060-018-2757-0

Abstract: Cross-talk between competitive endogenous RNAs (ceRNAs) may play a critical role in revealing potential mechanisms of tumor development and physiology. Glioblastoma is the most common type of malignant primary brain tumor, and the mechanisms of… read more here.

Keywords: rna; analyzing interactions; lncrnas circrnas; mirnas lncrnas ... See more keywords
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ceRNA network development and tumor-infiltrating immune cell analysis in hepatocellular carcinoma

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Published in 2021 at "Medical Oncology"

DOI: 10.1007/s12032-021-01534-6

Abstract: Hepatocellular carcinoma (HCC) is among the primary causes of cancer deaths globally. Despite efforts to understand liver cancer, its high morbidity and mortality remain high. Herein, we constructed two nomograms based on competing endogenous RNA… read more here.

Keywords: analysis; cerna network; cell; tumor ... See more keywords
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Comprehensive analysis of lncRNA-associated ceRNA network in colorectal cancer.

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Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.11.151

Abstract: Colorectal cancer (CRC) is one of the most common malignancies and morbidity and mortality are increasing rapidly. Increasing evidence showed the close correlation between aberrant expression of certain RNAs and the occurrence and development of… read more here.

Keywords: analysis; colorectal cancer; cerna network; cancer ... See more keywords
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Identify Functional lncRNAs in Nonalcoholic Fatty Liver Disease by Constructing a ceRNA Network

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Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.2c01801

Abstract: Aim: To identify functional long noncoding RNAs (lncRNAs) by constructing a NAFLD-related lncRNA–miRNA–mRNA network (NLMMN) based on the hypothesis that lncRNAs, as competitive endogenous RNAs (ceRNAs), are able to regulate mRNA functions by competitive binding… read more here.

Keywords: hepg2 cells; identify functional; functional lncrnas; cerna network ... See more keywords
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Analysis of Genetic Variants and the ceRNA Network of miR-9 in Non-Small Cell Lung Cancer.

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Published in 2022 at "DNA and cell biology"

DOI: 10.1089/dna.2021.0549

Abstract: Objective: To explore the role of single-nucleotide polymorphisms (SNPs) in hsa-miR-9 in non-small cell lung cancer (NSCLC). Methods: Log-rank and Cox regression analyses were conducted to assess the association of four functional SNPs of miR-9… read more here.

Keywords: lung cancer; cell; cerna network; lung ... See more keywords
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LncRNA-mediated ceRNA network was identified as a crucial determinant of differential effects in periodontitis and periimplantitis by high-throughput sequencing.

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Published in 2020 at "Clinical implant dentistry and related research"

DOI: 10.1111/cid.12911

Abstract: BACKGROUND AND OBJECTIVE Although periimplantitis and periodontitis share similar features, particularly clinical features, they are two different diseases and should be analyzed separately. Thus far, few omics-level differences in periimplantitis and periodontitis have been reported.… read more here.

Keywords: hsa mir; differential effects; cerna network; hsa ... See more keywords
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Integrated analysis of co‐expression and ceRNA network identifies five lncRNAs as prognostic markers for breast cancer

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Published in 2019 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.14721

Abstract: Long non‐coding RNAs (lncRNAs), which competitively bind miRNAs to regulate target mRNA expression in the competing endogenous RNAs (ceRNAs) network, have attracted increasing attention in breast cancer research. We aim to find more effective therapeutic… read more here.

Keywords: analysis; breast cancer; cerna network; expression ... See more keywords