vFLIP-regulated competing endogenous RNA (ceRNA) networks targeting lytic induction for KSHV-associated malignancies.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medical virology"
DOI: 10.1002/jmv.27654
Abstract: Kaposi's sarcoma-associated herpesvirus (KSHV) causes life-long latent infection and malignancies, including Kaposi sarcoma (KS) commonly found in AIDS patients. Lytic replication can be induced to kill tumor cells harboring latent KSHV, through viral cytopathic effects… read more here.
Keywords: associated malignancies; cerna networks; mir; kshv associated ... See more keywords
Constructing Integrative Cerna Networks and Finding Prognostic Biomarkers in Renal Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "IEEE/ACM transactions on computational biology and bioinformatics"
DOI: 10.1109/tcbb.2022.3214190
Abstract: Inspired by a newly discovered gene regulation mechanism known as competing endogenous RNA (ceRNA) interactions, several computational methods have been proposed to generate ceRNA networks. However, most of these methods have focused on deriving restricted… read more here.
Keywords: cell carcinoma; renal cell; prognostic biomarkers; cerna ... See more keywords
Potential Prognostic Biomarkers of Lung Adenocarcinoma Based on Bioinformatic Analysis
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/8859996
Abstract: Lung adenocarcinoma (LUAD), which accounts for 60% of non-small-cell lung cancers, is poorly diagnosed and has a low average 5-year survival rate (approximately 20%). It remains the leading cause of cancer-related deaths worldwide. Studies on… read more here.
Keywords: lung adenocarcinoma; analysis; cerna networks; prognostic biomarkers ... See more keywords
Identification and characterization of ncRNA-associated ceRNA networks in Arabidopsis leaf development
Sign Up to like & getrecommendations! Published in 2018 at "BMC Genomics"
DOI: 10.1186/s12864-018-4993-2
Abstract: BackgroundLeaf development is a complex biological process that is accompanied by wide transcriptional changes. Many protein-coding genes have been characterized in plant leaves, but little attention has been given to noncoding RNAs (ncRNAs). Moreover, increasing… read more here.
Keywords: leaf development; cerna networks; plant leaves; networks arabidopsis ... See more keywords
ceRNA network analysis reveals AP-1 transcription factor components as potential biomarkers for Alzheimer's disease.
Sign Up to like & getrecommendations! Published in 2022 at "Current Alzheimer research"
DOI: 10.2174/1567205019666220613142303
Abstract: BACKGROUND Alzheimer's disease (AD) is a progressive neurodegenerative disease affecting the elderly, characterized by decreased cognitive function. Non-coding RNAs contribute to AD pathogenesis. OBJECTIVE To identify potential therapeutic targets for AD, competing endogenous RNA (ceRNA)… read more here.
Keywords: transcription; disease; cerna; cerna networks ... See more keywords
The Functional Characterization of Epigenetically Related lncRNAs Involved in Dysregulated CeRNA–CeRNA Networks Across Eight Cancer Types
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.649755
Abstract: Numerous studies have demonstrated that lncRNAs could compete with other RNAs to bind miRNAs, as competing endogenous RNAs (ceRNAs), to regulate each other. On the other hand, ceRNAs were found to be recurrently dysregulated in… read more here.
Keywords: cancer types; eight cancer; cerna networks; cancer ... See more keywords
The Construction and Analysis of Infiltrating Immune Cell and ceRNA Networks in Diabetic Foot Ulcer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.836152
Abstract: Background Diabetic foot ulcer (DFU) is a severe complication characterized by low-grade infectious inflammation and probably associated with specific competitive endogenous RNAs (ceRNAs) and infiltrating immune cells. Nonetheless, no reliable biomarkers are used for detecting… read more here.
Keywords: diabetic foot; infectious inflammation; expression; foot ulcer ... See more keywords
LncRNA–miRNA–mRNA Networks of Gastrointestinal Cancers Representing Common and Specific LncRNAs and mRNAs
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.791919
Abstract: Gastrointestinal (GI) cancers are responsible for approximately half of cancer-related deaths, highlighting the need for the identification of distinct and common features in their clinicopathological characteristics. Long ncRNA (lncRNAs), which are involved in competitive endogenous… read more here.
Keywords: cancer; lncrna mirna; analysis; cerna networks ... See more keywords
Age-related ceRNA networks in adult Drosophila ageing
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1096902
Abstract: As Drosophila is an extensively used genetic model system, understanding of its regulatory networks has great significance in revealing the genetic mechanisms of ageing and human diseases. Competing endogenous RNA (ceRNA)-mediated regulation is an important… read more here.
Keywords: age related; cerna networks; dme mir; dme ... See more keywords
Differentially expressed genes, lncRNAs, and competing endogenous RNAs in Kawasaki disease
Sign Up to like & getrecommendations! Published in 2021 at "PeerJ"
DOI: 10.7717/peerj.11169
Abstract: Background Kawasaki disease (KD) is an acute and febrile systemic vasculitis of unknown etiology. This study aimed to identify the competing endogenous RNA (ceRNA) networks of lncRNAs, miRNAs, and genes in KD and explore the… read more here.
Keywords: hsa mir; cerna networks; kawasaki disease; differentially expressed ... See more keywords