Systematic review of computational methods for identifying miRNA-mediated RNA-RNA crosstalk
Sign Up to like & getrecommendations! Published in 2019 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbx137
Abstract: Posttranscriptional crosstalk and communication between RNAs yield large regulatory competing endogenous RNA (ceRNA) networks via shared microRNAs (miRNAs), as well as miRNA synergistic networks. The ceRNA crosstalk represents a novel layer of gene regulation that… read more here.
Keywords: rna; cerna; cerna regulation; crosstalk ... See more keywords
Comprehensive Analysis of ceRNA Regulation Network Involved in the Development of Coronary Artery Disease
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/6658115
Abstract: Background Coronary artery disease (CAD) is one of the most common causes of sudden death with high morbidity in recent years. This paper is aimed at exploring the early peripheral blood biomarkers of sudden death… read more here.
Keywords: network; coronary artery; cerna; cerna regulation ... See more keywords
Competing Endogenous RNA Regulations in Neurodegenerative Disorders: Current Challenges and Emerging Insights
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2018.00370
Abstract: The past decade has witnessed exciting breakthroughs that have contributed to the richness and complexity of a burgeoning modern RNA world, and one particular breakthrough—the competing endogenous RNA (ceRNA) hypothesis—has been described as the “Rosetta… read more here.
Keywords: endogenous rna; neurodegenerative disorders; cerna; cerna regulation ... See more keywords
Screening of core genes and prediction of ceRNA regulation mechanism of circRNAs in nasopharyngeal carcinoma by bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2023 at "Pathology and Oncology Research"
DOI: 10.3389/pore.2023.1610960
Abstract: Background: Nasopharyngeal carcinoma (NPC) represents a highly aggressive malignant tumor. Competing endogenous RNAs (ceRNA) regulation is a common regulatory mechanism in tumors. The ceRNA network links the functions between mRNAs and ncRNAs, thus playing an… read more here.
Keywords: gene; analysis; cerna regulation; mechanism ... See more keywords