Modulation of cerulein‐induced pancreatic inflammation by hydroalcoholic extract of curry leaf (Murraya koenigii)
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6344
Abstract: This study was performed to study the in vitro and in vivo efficacy of hydroalcoholic extract of curry leaf (CLE) rich in carbazole alkaloids, against LPS‐induced inflammation in Raw 264.7 macrophages and cerulein‐induced acute pancreatitis,… read more here.
Keywords: hydroalcoholic extract; inflammation; cle; cerulein induced ... See more keywords
Eupatilin Ameliorates Cerulein-Induced Pancreatitis Via Inhibition of the Protein Kinase D1 Signaling Pathway In Vitro.
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DOI: 10.1097/mpa.0000000000001488
Abstract: OBJECTIVE The aim of this study was to investigate the effects of eupatilin on protein kinase D1 (PKD1) and nuclear factor kappa B (NF-κB) signaling pathways in cerulein-induced in vitro pancreatitis. METHODS We used collagenase… read more here.
Keywords: pancreatitis; cerulein induced; eupatilin; protein kinase ... See more keywords
Hic‐5 deficiency protects cerulein‐induced chronic pancreatitis via down‐regulation of the NF‐κB (p65)/IL‐6 signalling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14833
Abstract: Chronic pancreatitis (CP), characterized by pancreatic fibrosis, is a recurrent, progressive and irreversible disease. Activation of the pancreatic stellate cells (PSCs) is considered a core event in pancreatic fibrosis. In this study, we investigated the… read more here.
Keywords: signalling pathway; p65 signalling; chronic pancreatitis; cerulein induced ... See more keywords
Superoxide dismutase mimetic nanoceria restrains cerulein induced acute pancreatitis.
Sign Up to like & getrecommendations! Published in 2019 at "Nanomedicine"
DOI: 10.2217/nnm-2018-0318
Abstract: Aim: The present study was carried out to assess the effect of nanoceria (NC) on pancreatic inflammation caused by cerulein. Methods: NC was characterized and in vitro studies were carried out in murine macrophages. The… read more here.
Keywords: pancreatitis; mimetic nanoceria; dismutase mimetic; cerulein induced ... See more keywords
Glyoxalase-I Is Upregulated in Acute Cerulein-Induced Pancreatitis: A New Mechanism in Pancreatic Inflammation?
Sign Up to like & getrecommendations! Published in 2021 at "Antioxidants"
DOI: 10.3390/antiox10101574
Abstract: Inflammation caused by oxidative stress (ROS) demonstrates an essential mechanism in the pathogenesis of acute pancreatitis (AP). Important sources for ROS comprise the reactive compound methylglyoxal (MGO) itself and the MGO-derived formation of advanced glycation… read more here.
Keywords: mgo; glo; mechanism; ar42j cells ... See more keywords
Repetitive Cerulein-Induced Chronic Pancreatitis in Growing Pigs—A Pilot Study
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DOI: 10.3390/ijms24097715
Abstract: Chronic pancreatitis (CP) is an irreversible and progressive inflammatory disease. Knowledge on the development and progression of CP is limited. The goal of the study was to define the serum profile of pro-inflammatory cytokines and… read more here.
Keywords: growing pigs; cerulein induced; chronic pancreatitis; repetitive cerulein ... See more keywords
Docosahexaenoic Acid Inhibits Cerulein-Induced Acute Pancreatitis in Rats
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DOI: 10.3390/nu9070744
Abstract: Oxidative stress is an important regulator in the pathogenesis of acute pancreatitis (AP). Reactive oxygen species induce activation of inflammatory cascades, inflammatory cell recruitment, and tissue damage. NF-κB regulates inflammatory cytokine gene expression, which induces… read more here.
Keywords: acute pancreatitis; pancreatitis; inhibits cerulein; docosahexaenoic acid ... See more keywords
Hydroalcoholic extract of licorice (Glycyrrhiza glabra L.) root attenuates ethanol and cerulein induced pancreatitis in rats
Sign Up to like & getrecommendations! Published in 2019 at "Asian Pacific Journal of Tropical Biomedicine"
DOI: 10.4103/2221-1691.269524
Abstract: Objective: To evaluate the therapeutic potential of hydroalcoholic extract of licorice root against ethanol and cerulein induced chronic pancreatitis in rats. Methods: The phytochemical profile of hydroalcoholic extract of licorice root was determined by high… read more here.
Keywords: hydroalcoholic extract; ethanol cerulein; root; extract licorice ... See more keywords