Clustering patterns of type‐type combination in multiple genotypes infections of human papillomavirus in cervical adenocarcinoma
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DOI: 10.1002/jmv.25553
Abstract: Coinfections with multiple types of human papillomavirus (HPV) occur in cervical adenocarcinoma (ADC). However, it remains unclear the clustering patterns of multiple types in HPV coinfections and relevant factors in ADC. A total of 718… read more here.
Keywords: hpv coinfections; cervical adenocarcinoma; hpv; human papillomavirus ... See more keywords
Single‐cell transcriptomics dissects epithelial heterogeneity in HPV+ cervical adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28480
Abstract: The intra‐ and intertumoral heterogeneity of epithelial cells in human papillomavirus (HPV+) cervical adenocarcinoma (CEAD) remains largely unknown. To investigate this issue, we performed single‐cell RNA sequencing on 19 229 epithelial cells sorted from three tumor… read more here.
Keywords: heterogeneity; cervical adenocarcinoma; single cell; highly enriched ... See more keywords
Ovarian conservation is associated with better survival in young patients with T1N0M0 cervical adenocarcinoma: a population-based study
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-018-4674-z
Abstract: PurposeOvarian conservation is controversial in patients with cervical adenocarcinoma due to the risk of ovarian metastasis. The aim of this study is to evaluate the association of ovarian conservation with survival outcomes in young patients… read more here.
Keywords: ovarian conservation; young patients; conservation; cervical adenocarcinoma ... See more keywords
Oncologic outcomes of patients with FIGO 2014 stage IB-IIA cervical adenocarcinoma who underwent radical surgery
Sign Up to like & getrecommendations! Published in 2022 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-022-06507-2
Abstract: To identify prognostic factors of early-stage cervical adenocarcinoma in patients with FIGO IB–IIA, who were treated with radical surgery. Clinical data of 64 patients with stage IB–IIA cervical adenocarcinoma who underwent radical hysterectomy and lymphadenectomy… read more here.
Keywords: prognostic factors; recurrence; adenocarcinoma; patients figo ... See more keywords
Clinicopathological characteristics and prognostic factors of cervical adenocarcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-86786-y
Abstract: We aimed to assess the clinicopathological features and to determine the prognostic factors of cervical adenocarcinoma (AC). Relevant data were extracted from surveillance, epidemiology and end results database from 2004 to 2015. The log-rank test… read more here.
Keywords: prognostic factors; figo stage; cervical adenocarcinoma; factors cervical ... See more keywords
P16INK4A expression might be associated with a favorable prognosis for cervical adenocarcinoma via dysregulation of the RB pathway
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-97703-8
Abstract: Previous studies have largely failed to clarify the relationship between p16INK4A status and cervical adenocarcinoma prognosis. The current study aimed to examine the clinical and pathological significance of p16INK4A expression in several cervical adenocarcinoma subtypes.… read more here.
Keywords: prognosis; cervical adenocarcinoma; expression; p16ink4a expression ... See more keywords
Bioinformatics analysis of methylation in cervical adenocarcinoma in Xinjiang, China
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DOI: 10.1097/md.0000000000012108
Abstract: Abstract This study is to investigate the genomic methylation in cervical adenocarcinoma in Xinjiang, China, using the DNA methylation analysis chips. Methylation of 5 cases of cervical adenocarcinoma tissues and 5 cases of normal cervical… read more here.
Keywords: analysis; cervical adenocarcinoma; methylation cervical; xinjiang china ... See more keywords
Development of an in vitro carcinogenesis model of human papillomavirus‐induced cervical adenocarcinoma
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DOI: 10.1111/cas.15246
Abstract: Cervical adenocarcinoma (ADC) is the second most common pathological subtype of cervical cancer after squamous cell carcinoma. It accounts for approximately 20% of cervical cancers, and the incidence has increased in the past few decades,… read more here.
Keywords: carcinogenesis; human papillomavirus; squamous cell; model ... See more keywords
Aberrant expression of claudin‐6 contributes to malignant potentials and drug resistance of cervical adenocarcinoma
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DOI: 10.1111/cas.15284
Abstract: Recent studies have revealed that aberrant expression of tight junction (TJ) proteins is a hallmark of various solid tumors and it is recognized as a useful therapeutic target. Claudin‐6 (CLDN6), a member of the family… read more here.
Keywords: cell; malignant potentials; expression; cervical adenocarcinoma ... See more keywords
Cervical adenocarcinoma: integration of HPV status, pattern of invasion, morphology and molecular markers into classification
Sign Up to like & getrecommendations! Published in 2020 at "Histopathology"
DOI: 10.1111/his.13995
Abstract: Cervical adenocarcinoma is a heterogenous group of tumours with various aetiologies, molecular drivers, morphologies, response to treatment and prognosis. It has become evident that human papillomavirus (HPV) infection does not drive all adenocarcinomas, and appropriate… read more here.
Keywords: cervical adenocarcinoma; classification; hpv; morphology molecular ... See more keywords
PD‐L1 expression and immune stromal features in HPV‐independent cervical adenocarcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Histopathology"
DOI: 10.1111/his.14435
Abstract: Human papilloma virus (HPV)‐independent cervical adenocarcinoma (CA) is usually diagnosed at an advanced stage, while the therapeutic options are limited. Therefore, effective treatment options are required. The programmed cell death 1 (PD‐1) inhibitor pembrolizumab has… read more here.
Keywords: hpv independent; independent cervical; cervical adenocarcinoma; expression ... See more keywords