[Place of PARP inhibitors in the treatment of endometrial and cervical cancers].
Sign Up to like & getrecommendations! Published in 2021 at "Bulletin du cancer"
DOI: 10.1016/j.bulcan.2021.09.011
Abstract: New molecular therapeutic approaches have emerged in recent years for advanced gynaecological cancers, including targeted therapies such as poly-ADP-ribose polymerase inhibitors (PARPi). These have demonstrated efficacy in high-grade serous ovarian cancers in patients carrying a… read more here.
Keywords: parp inhibitors; cervical cancers; endometrial cervical; place parp ... See more keywords
Surgical staging identified false HPV-negative cases in a large series of invasive cervical cancers
Sign Up to like & getrecommendations! Published in 2017 at "Papillomavirus Research"
DOI: 10.1016/j.pvr.2017.10.003
Abstract: Objective We examined a large series of biopsy-proven invasive cervical cancers with surgical staging and HPV re-testing to estimate the relevance of HPV-negative cervical cancers in a Caucasian population. Methods We prospectively collected smears from… read more here.
Keywords: surgical staging; cervical cancers; negative cases; cervical cancer ... See more keywords
Deep sequencing detects human papillomavirus (HPV) in cervical cancers negative for HPV by PCR
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Cancer"
DOI: 10.1038/s41416-020-01111-0
Abstract: Background Human papillomavirus (HPV) is a necessary cause of cervical cancer, although some invasive cervical cancers may test negative by HPV PCR. We previously requested all invasive cervical cancers in Sweden during 10 years and… read more here.
Keywords: cervical cancers; deep sequencing; hpv; hpv pcr ... See more keywords
Autodelineation of cervical cancers using multiparametric magnetic resonance imaging and machine learning
Sign Up to like & getrecommendations! Published in 2017 at "Acta Oncologica"
DOI: 10.1080/0284186x.2017.1285499
Abstract: Abstract Background: Tumour delineation is a challenging, time-consuming and complex part of radiotherapy planning. In this study, an automatic method for delineating locally advanced cervical cancers was developed using a machine learning approach. Materials and… read more here.
Keywords: machine; machine learning; cervical cancers; magnetic resonance ... See more keywords
Glutaminase Inhibitors Induce Thiol-Mediated Oxidative Stress and Radiosensitization in Treatment-Resistant Cervical Cancers
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DOI: 10.1158/1535-7163.mct-20-0271
Abstract: The purpose of this study was to determine if radiation (RT)-resistant cervical cancers are dependent upon glutamine metabolism driven by activation of the PI3K pathway and test whether PI3K pathway mutation predicts radiosensitization by inhibition… read more here.
Keywords: cervical cancers; treatment; resistant cervical; cancer ... See more keywords
Histogram analysis of apparent diffusion coefficient for monitoring early response in patients with advanced cervical cancers undergoing concurrent chemo-radiotherapy
Sign Up to like & getrecommendations! Published in 2017 at "Acta Radiologica"
DOI: 10.1177/0284185117694509
Abstract: Background Apparent diffusion coefficient (ADC) histogram analysis has been widely used in determining tumor prognosis. Purpose To investigate the dynamic changes of ADC histogram parameters during concurrent chemo-radiotherapy (CCRT) in patients with advanced cervical cancers.… read more here.
Keywords: histogram; response; cervical cancers; ccrt ... See more keywords
Efficient mutation screening for cervical cancers from circulating tumor DNA in blood
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DOI: 10.1186/s12885-020-07161-0
Abstract: Background Early diagnosis and continuous monitoring are necessary for an efficient management of cervical cancers (CC). Liquid biopsy, such as detecting circulating tumor DNA (ctDNA) from blood, is a simple, non-invasive method for testing and… read more here.
Keywords: cervical cancers; circulating tumor; blood; panel ... See more keywords
Women’s knowledge, attitudes and practices (KAP) relating to breast and cervical cancers in rural Zimbabwe: a cross sectional study in Mudzi District, Mashonaland East Province
Sign Up to like & getrecommendations! Published in 2019 at "BMC Public Health"
DOI: 10.1186/s12889-018-6333-5
Abstract: BackgroundBreast and cervical cancers constitute the most common cancers among women in sub-Saharan Africa. In Zimbabwe, cervical cancer accounts for more than a third of all cancers among women of African descent. Cancer knowledge levels,… read more here.
Keywords: attitudes practices; cervical cancers; cervical cancer; zimbabwe ... See more keywords
Male involvement in female partners’ screening for breast and cervical cancers in Southwest Nigeria
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DOI: 10.1371/journal.pone.0284141
Abstract: Background Breast and cervical cancers are in the top 10 most common cancers in women globally and the most common cancers in Nigerian women. The incidences have been rising steadily over the years. Involvement of… read more here.
Keywords: breast cervical; female partners; cervical cancers; male involvement ... See more keywords
The ‘Why and How’ of Cervical Cancers and Genital HPV Infection
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DOI: 10.25259/cmas_03_03_2021
Abstract: Knowing about the virology of human papillomavirus (HPV) including its structure, functions and mechanism of infection, helps in understanding the disease process and morphology of precancerous lesions for cervical cancer. Two types of HPV, low-… read more here.
Keywords: virology; cancers genital; infection; cervical cancers ... See more keywords
Subtyping of Human Papillomavirus-Positive Cervical Cancers Based on the Expression Profiles of 50 Genes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.801639
Abstract: Background Human papillomavirus-positive (HPV+) cervical cancers are highly heterogeneous in molecular and clinical features. However, the molecular classification of HPV+ cervical cancers remains insufficiently unexplored. Methods Based on the expression profiles of 50 genes having… read more here.
Keywords: cervical cancers; expression profiles; hpv cervical; based expression ... See more keywords