Protein and peptide engineering for CEST imaging in the age of Synthetic Biology.
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DOI: 10.1002/nbm.4712
Abstract: At the beginning of the millennium, the first Chemical Exchange Saturation Transfer (CEST) contrast agents were bio-organic molecules. However, later, metal based CEST agents (paraCEST agents) took center stage. This didn't last too long as… read more here.
Keywords: synthetic biology; cest contrast; biology; cest agents ... See more keywords
Monitor Tumor pHe and Response Longitudinally during Treatment Using CEST MRI-Detectable Alginate Microbeads
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DOI: 10.1021/acsami.2c10493
Abstract: Imaging pHe of the tumor microenvironment has paramount importance for characterizing aggressive, invasive tumors, as well as therapeutic responses. Here, a robust approach to image pH changes in the tumor microenvironment longitudinally and during sodium… read more here.
Keywords: phe; cest contrast; treatment; tumor ... See more keywords