LAUSR

Multislice CEST MRI improves the spatial assessment of tumor pH

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1 Published in 2017 at "Magnetic Resonance in Medicine"

DOI: 10.1002/mrm.26348

Abstract: Multislice maps of extracellular pH (pHe) are needed to interrogate the heterogeneities of tumors and normal organs. To address this need, we have developed a multislice chemical exchange saturation transfer (CEST) MRI acquisition method with… read more here.

Keywords: cest mri; multislice cest; mri improves; multislice ... See more keywords

Establishing upper limits on neuronal activity–evoked pH changes with APT‐CEST MRI at 7 T

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1 Published in 2018 at "Magnetic Resonance in Medicine"

DOI: 10.1002/mrm.27013

Abstract: To detect neuronal activity–evoked pH changes by amide proton transfer–chemical exchange saturation transfer (APT‐CEST) MRI at 7 T. read more here.

Keywords: cest mri; neuronal activity; activity evoked; apt cest ... See more keywords

Noninvasive imaging of renal urea handling by CEST‐MRI

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1 Published in 2019 at "Magnetic Resonance in Medicine"

DOI: 10.1002/mrm.27968

Abstract: Renal function is characterized by concentration of urea for removal in urine. We tested urea as a CEST‐MRI contrast agent for measurement of the concentrating capacity of distinct renal anatomical regions. read more here.

Keywords: cest mri; urea handling; noninvasive imaging; imaging renal ... See more keywords

Whole‐brain quantitative CEST MRI at 7T using parallel transmission methods and B1+ correction

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1 Published in 2021 at "Magnetic Resonance in Medicine"

DOI: 10.1002/mrm.28745

Abstract: To enable whole‐brain quantitative CEST MRI at ultra‐high magnetic field strengths (B0 ≥ 7T) within short acquisition times. read more here.

Keywords: brain quantitative; cest mri; quantitative cest; whole brain ... See more keywords

Clinically compatible subject‐specific dynamic parallel transmit pulse design for homogeneous fat saturation and water‐excitation at 7T: Proof‐of‐concept for CEST MRI of the brain

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1 Published in 2022 at "Magnetic Resonance in Medicine"

DOI: 10.1002/mrm.29412

Abstract: To evaluate the benefits and challenges of dynamic parallel transmit (pTx) pulses for fat saturation (FS) and water‐excitation (WE), in the context of CEST MRI. read more here.

Keywords: fat saturation; parallel transmit; dynamic parallel; cest mri ... See more keywords

Free‐breathing 3D CEST MRI of human liver at 3.0 T

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1 Published in 2022 at "Magnetic Resonance in Medicine"

DOI: 10.1002/mrm.29470

Abstract: To develop a novel 3D abdominal CEST MRI technique at 3 T using MR multitasking, which enables entire‐liver coverage with free‐breathing acquisition. read more here.

Keywords: free breathing; mri human; cest mri; breathing cest ... See more keywords

DeepCEST 7 T: Fast and homogeneous mapping of 7 T CEST MRI parameters and their uncertainty quantification

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2 Published in 2022 at "Magnetic Resonance in Medicine"

DOI: 10.1002/mrm.29520

Abstract: In this work, we investigated the ability of neural networks to rapidly and robustly predict Lorentzian parameters of multi‐pool CEST MRI spectra at 7 T with corresponding uncertainty maps to make them quickly and easily… read more here.

Keywords: uncertainty; cest mri; mri; deepcest fast ... See more keywords

Dual assessment of kidney perfusion and pH by exploiting a dynamic CEST‐MRI approach in an acute kidney ischemia–reperfusion injury murine model

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1 Published in 2020 at "NMR in Biomedicine"

DOI: 10.1002/nbm.4287

Abstract: Several factors can lead to acute kidney injury, but damage following ischemia and reperfusion injuries is the main risk factor and usually develops into chronic disease. MRI has often been proposed as a method with… read more here.

Keywords: cest mri; perfusion; acute kidney; mri ... See more keywords

Demonstration of pH imaging in acute stroke with endogenous ratiometric CEST MRI at 2ppm.

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2 Published in 2022 at "NMR in biomedicine"

DOI: 10.1002/nbm.4850

Abstract: pH change is often considered a hallmark of metabolic disruption in diseases such as ischemic stroke and cancer. Chemical exchange saturation transfer (CEST) MRI, particularly amide proton transfer (APT), has emerged as a noninvasive pH… read more here.

Keywords: ratiometric cest; cest; cest mri; acute stroke ... See more keywords

CEST‐MRI for body oncologic imaging: are we there yet?

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1 Published in 2023 at "NMR in Biomedicine"

DOI: 10.1002/nbm.4906

Abstract: Chemical exchange saturation transfer (CEST) MRI has gained recognition as a valuable addition to the molecular imaging and quantitative biomarker arsenal, especially for characterization of brain tumors. There is also increasing interest in the use… read more here.

Keywords: oncology; cest mri; mri; body oncologic ... See more keywords

Analysis Protocol for the Quantification of Renal pH Using Chemical Exchange Saturation Transfer (CEST) MRI.

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1 Published in 2021 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-0978-1_40

Abstract: The kidney plays a major role in maintaining body pH homeostasis. Renal pH, in particular, changes immediately following injuries such as intoxication and ischemia, making pH an early biomarker for kidney injury before the symptom… read more here.

Keywords: cest mri; chemical exchange; analysis; mri ... See more keywords