Can we revive CETP-inhibitors for the prevention of cardiovascular disease?
Sign Up to like & getrecommendations! Published in 2022 at "Current opinion in lipidology"
DOI: 10.1097/mol.0000000000000854
Abstract: PURPOSE OF REVIEW To review recent developments in the field of cholesteryl ester transfer protein (CETP) inhibition from clinical trials and genomic analyses which have the potential to impact future clinical programs. RECENT FINDINGS CETP… read more here.
Keywords: prevention cardiovascular; cardiovascular disease; cetp; cetp inhibitors ... See more keywords
Synthesis, Molecular Modeling and Biological Evaluation of Novel Trifluoromethyl Benzamides as Promising CETP Inhibitors.
Sign Up to like & getrecommendations! Published in 2023 at "Current computer-aided drug design"
DOI: 10.2174/1573409919666230509123852
Abstract: BACKGROUND Hyperlipidemia is considered a major risk factor for the progress of atherosclerosis. OBJECTIVE Cholesteryl ester transfer protein (CETP) facilitates the relocation of cholesterol esters from HDL to LDL. CETP inhibition produces higher HDL and… read more here.
Keywords: modeling biological; biological evaluation; cetp; synthesis molecular ... See more keywords