Regioselective Intermolecular Hydroamidation of β‐CF3‐1,3‐enynamides: An Approach to Tri‐substituted γ‐CF3‐allenamides
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202400674
Abstract: A simple base mediated, highly regioselective 1,4‐hydroamidation of β‐CF3‐1,3‐enynamides with secondary amides for synthesis of tri‐substituted γ‐CF3‐allenamides compounds was developed. N‐alkyl sulfonamides are generally good candidates for the present transformation. γ‐CF3‐allenamides could be employed for synthesis of potential… read more here.
Keywords: substituted cf3; cf3 enynamides; cf3; cf3 allenamides ... See more keywords
Atmospheric oxidation chemistry of hexafluoroisobutylene initiated by OH radical: Kinetics and mechanism
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Theoretical Chemistry"
DOI: 10.1016/j.comptc.2020.113137
Abstract: Abstract Kinetics and mechanism for the gas-phase reaction of (CF3)2C = CH2 and OH radicals in the absence and presence of O2/NO have been investigated by G3(MP2)//B3PW91/6-311++G(d,p) method. The results showed the OH radical favored to attack… read more here.
Keywords: kinetics mechanism; cf3; chemistry; cf3 ch2 ... See more keywords
Reaction of CF3-ynones with methyl thioglycolate. Regioselective synthesis of 3-CF3-thiophene derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2018.07.013
Abstract: Abstract Efficient regioselective synthesis of 3-CF3-substituted thiophene derivatives was elaborated using addition of methyl thioglycolate to CF3-ynones in the presence of sodium methoxide. read more here.
Keywords: cf3 ynones; cf3; synthesis cf3; thiophene derivatives ... See more keywords
Partially fluorinated Scorpionate [HB(3-(CF3),5-(Ph)Pz)3]− as a supporting ligand for silver(I)-benzene, -carbonyl, and -PPh3 complexes
Sign Up to like & getrecommendations! Published in 2017 at "Polyhedron"
DOI: 10.1016/j.poly.2016.09.014
Abstract: Abstract The benzene, CO, and PPh3 adducts [HB(3-(CF3),5-(Ph)Pz)3]AgL (L = C6H6, CO, or PPh3) have been synthesized by a metathesis process using [HB(3-(CF3),5-(Ph)Pz)3]Na(THF), CF3SO3Ag, and the corresponding co-ligands. These silver(I) adducts have been characterized by NMR spectroscopy,… read more here.
Keywords: partially fluorinated; pph3; fluorinated scorpionate; cf3 ... See more keywords
Synthesis, characterization, DFT and biological activity of oligothiophene β-diketone and Cu-complexes
Sign Up to like & getrecommendations! Published in 2021 at "Polyhedron"
DOI: 10.1016/j.poly.2021.115290
Abstract: Abstract The chemical reactivity and antimicrobial activity of [CuII((CF3)COCHCO(C4H2S)(C4H3S))2] is presented. A density functional theory (DFT) study of the oligothiophene-containing bis(β-diketonato)copper(II) compound [CuII((CF3)COCHCO(C4H2S)(C4H3S))2] shows that the molecule has a square planar geometry around the copper,… read more here.
Keywords: copper; activity; cuii cf3; reduction ... See more keywords
Wavelength-Dependent UV-LED Photolysis of Fluorinated Pesticides and Pharmaceuticals.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental science & technology"
DOI: 10.1021/acs.est.3c00627
Abstract: The wavelength dependence of photoproduct formation and quantum yields was evaluated for fluorinated pesticides and pharmaceuticals using UV-light emitting diodes (LEDs) with 255, 275, 308, 365, and 405 nm peak wavelengths. The fluorinated compounds chosen… read more here.
Keywords: dependent led; fluorinated pesticides; wavelength dependent; cf3 ... See more keywords
FeCl2·4H2O-Mediated Conversion of the CF3 Group into a Series of Esters: A Strategy for the Synthesis of FeII Complexes with In Situ-Formed Ester-Containing Ligands.
Sign Up to like & getrecommendations! Published in 2025 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.4c04876
Abstract: A practical strategy for the preparation of a series of iron(II) complexes has been developed. This methodology features in situ esterification of the CF3 group on the backbone of the PIP-CF3 ligand (HPIP = 3-(pyridin-2-yl)imidazo[1,5-a]pyridine,… read more here.
Keywords: pip; esterification; pip cf3; cf3 group ... See more keywords
Diazotrifluoroethyl Radical: A CF3-Containing Building Block in [3 + 2] Cycloaddition.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c03603
Abstract: We present herein a visible-light-induced [3 + 2] cycloaddition of a hypervalent iodine(III) reagent with α-ketoacids for the construction of 5-CF3-1,3,4-oxadiazoles that are of importance in medicinal chemistry. The reaction proceeds smoothly without a photocatalyst,… read more here.
Keywords: cycloaddition; building block; containing building; cf3 ... See more keywords
Synthesis of Trifluoromethylated 4H-Pyran and 4H-Thiopyran via Divergent Reaction of β-CF3-1,3-Enynes with β-Ketothioamides.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03264
Abstract: A chemodivergent tandem intermolecular hydrocarbonation and intramolecular oxy- or thioheterocyclization sequence of β-CF3-1,3-enyne with β-ketothioamides (KTAs) leading to ring-trifluoromethylated 4H-pyran or 4H-thiopyran, respectively, by the combined use of AgNO3 as a catalyst and Et3N as… read more here.
Keywords: trifluoromethylated pyran; pyran thiopyran; synthesis trifluoromethylated; cf3 ... See more keywords
Stereoselective Preparation of CF3-Containing Cyclopropanes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03714
Abstract: A regio- and diastereoselective carbometalation of easily accessible CF3-substituted cyclopropenes is developed with a diastereoselectivity of the addition opposite to the CF3 group. This simple strategy allows the preparation of polysubstituted (up to penta-) cyclopropyl… read more here.
Keywords: stereoselective preparation; cf3 containing; containing cyclopropanes; preparation ... See more keywords
A Photo- and Electrochemistry-Triggered Redox-Neutral Cyclization Strategy to Access Cyclic N-CF3 Amides.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c00355
Abstract: While the construction of N-CF3 amides has seen significant progress, the current synthetic repertoire is largely limited to noncyclic variants. Here, we report synthetic access to N-CF3 isoindolinones. The developed redox-neutral cyclization leverages amino acid-derived… read more here.
Keywords: redox neutral; cf3 amides; electrochemistry; access ... See more keywords