Regioselective Intermolecular Hydroamidation of β‐CF3‐1,3‐enynamides: An Approach to Tri‐substituted γ‐CF3‐allenamides
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DOI: 10.1002/ejoc.202400674
Abstract: A simple base mediated, highly regioselective 1,4‐hydroamidation of β‐CF3‐1,3‐enynamides with secondary amides for synthesis of tri‐substituted γ‐CF3‐allenamides compounds was developed. N‐alkyl sulfonamides are generally good candidates for the present transformation. γ‐CF3‐allenamides could be employed for synthesis of potential… read more here.
Keywords: substituted cf3; cf3 enynamides; cf3; cf3 allenamides ... See more keywords