CFAP65 is required in the acrosome biogenesis and mitochondrial sheath assembly during spermiogenesis.
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DOI: 10.1093/hmg/ddab185
Abstract: Asthenoteratospermia is a common cause of male infertility. Recent studies have revealed that CFAP65 mutations lead to severe asthenoteratospermia due to acrosome hypoplasia and flagellum malformations. However, the molecular mechanism underlying CFAP65-associated sperm malformation is… read more here.
Keywords: cfap65; spermiogenesis; acrosome biogenesis; mitochondrial sheath ... See more keywords