Resistance to Cefiderocol Involved Expression of PER-1 β-Lactamase and Downregulation of Iron Transporter System in Carbapenem-Resistant Acinetobacter baumannii
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DOI: 10.2147/idr.s392241
Abstract: Background Cefiderocol (CFDC) is a promising antimicrobial agent against multidrug resistant Gram-negative bacteria. However, CFDC resistance has emerged in carbapenem-resistant Acinetobacter baumannii (CR-AB) but the underlying mechanisms remain unclear. Methods Whole-genome sequencing and transcriptome sequencing… read more here.
Keywords: non susceptible; cfdc non; cfdc; susceptible isolates ... See more keywords