Clinical implications of circulating cell-free DNA quantification and metabolic tumor burden in advanced non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Lung cancer"
DOI: 10.1016/j.lungcan.2019.06.014
Abstract: OBJECTIVES This study unravels the significance of cell-free DNA (cfDNA) quantification as a promising measure of the biological behavior/aggressiveness of tumors. Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) measured by positron emission tomography/computed… read more here.
Keywords: cfdna; tumor burden; cell; cfdna levels ... See more keywords
Circulating cell-free DNA correlate to disease activity and treatment response of patients with radiographic axial spondyloarthritis
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DOI: 10.1038/s41598-023-50543-0
Abstract: Microdamage and its related inflammation contribute to the development of radiographic axial spondyloarthritis (r-axSpA). Inflammation and cell death in damaged tissues are associated with cell-free DNA (cfDNA) release. Here we investigated whether circulating cfDNA could… read more here.
Keywords: treatment; disease activity; cfdna levels; response ... See more keywords
Multiallelic Copy Number Variation in ORM1 is Associated with Plasma Cell-Free DNA Levels as an Intermediate Phenotype for Venous Thromboembolism
Sign Up to like & getrecommendations! Published in 2022 at "Thrombosis and Haemostasis"
DOI: 10.1055/s-0043-1760844
Abstract: Venous thromboembolism (VTE) is a common disease with high heritability. However, only a small portion of the genetic variance of VTE can be explained by known genetic risk factors. Neutrophil extracellular traps (NETs) have been… read more here.
Keywords: cfdna levels; cell free; cfdna; plasma cell ... See more keywords
Circulating extracellular DNA levels are acutely elevated in ischaemic stroke and associated with innate immune system activation
Sign Up to like & getrecommendations! Published in 2017 at "Brain Injury"
DOI: 10.1080/02699052.2017.1312018
Abstract: ABSTRACT Objective: The objective of this work was to assess the ability of peripheral blood cell-free DNA (cfDNA) levels to identify ischaemic stroke early in the acute phase of care, as well as to examine… read more here.
Keywords: cfdna levels; peripheral blood; blood; ischaemic stroke ... See more keywords
Assessment of dd-cfDNA Levels in Clinically Stable Lung Allograft Recipients Beyond the Initial 2 y Posttransplant
Sign Up to like & getrecommendations! Published in 2022 at "Transplantation Direct"
DOI: 10.1097/txd.0000000000001411
Abstract: Background. Donor-derived cell-free DNA (dd-cfDNA) is a useful biomarker for the diagnosis of acute allograft injury within the first 1 to 2 y after lung transplant, but its utility for diagnosing chronic lung allograft dysfunction… read more here.
Keywords: cfdna levels; clinically stable; cfdna; lung ... See more keywords
Admission Circulating Cell-Free DNA Levels as a Prognostic Factor in Pediatric Burns
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/5004282
Abstract: Background Burn injuries in children are a major physical and psychological trauma, often a severe condition with long-term consequences. Current methods of assessing the extent of burn injuries on admission are inaccurate. Circulating cell-free DNA… read more here.
Keywords: cfdna levels; pediatric burn; cfdna; circulating cell ... See more keywords
Role of cfDNA and DNA integrity index (DII) in colon cancer in response to surgery.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.4_suppl.236
Abstract: 236 Background: Colorectal cancer diagnosis requires new biomarkers for improved detection and monitoring. cfDNA has shown potential in detecting minimal residual disease, evaluating treatment response, and providing prognostic information. Recent studies highlight cfDNA as a… read more here.
Keywords: surgery; cancer; cfdna levels; response ... See more keywords
Endotheliopathy is associated with higher levels of cell-free DNA following major trauma: A prospective observational study
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DOI: 10.1371/journal.pone.0189870
Abstract: Background Cell free deoxyribonucleic acid (cfDNA) has been proposed as a biomarker of secondary complications following trauma. Raised thrombomodulin and syndecan-1 levels have been used to indicate endotheliopathy, and are associated with inflammation, coagulopathy, and… read more here.
Keywords: cfdna levels; cell free; trauma; cfdna ... See more keywords
Role of cell-free DNA levels in the diagnosis and prognosis of sepsis and bacteremia: A systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2024 at "PLOS ONE"
DOI: 10.1371/journal.pone.0305895
Abstract: Background Sepsis remains a major cause of mortality in intensive care units (ICUs). Prompt diagnosis and effective management are imperative for better outcomes. In this systematic review and meta-analysis, we explore the potential of circulating… read more here.
Keywords: meta analysis; cfdna levels; sepsis;