Pathophysiology of Cystic Fibrosis Liver Disease: A Channelopathy Leading to Alterations in Innate Immunity and in Microbiota
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2019.04.013
Abstract: Cystic fibrosis (CF) is a monogenic disease caused by mutation of Cftr. CF-associated liver disease (CFLD) is a common nonpulmonary cause of mortality in CF and accounts for approximately 2.5%–5% of overall CF mortality. The… read more here.
Keywords: cystic fibrosis; cfld; disease; liver disease ... See more keywords
Diagnosis, follow-up and treatment of cystic fibrosis-related liver disease
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Pulmonary Medicine"
DOI: 10.1097/mcp.0000000000000428
Abstract: Purpose of review To provide an insight and overview of the challenges in the diagnosis, follow-up and treatment of cystic fibrosis-related liver disease (CFLD). Recent findings The variable pathophysiology of CFLD complicates its diagnosis and… read more here.
Keywords: cystic fibrosis; cfld; treatment; related liver ... See more keywords
Non-invasive tools for detection of liver disease in children and adolescents with cystic fibrosis.
Sign Up to like & getrecommendations! Published in 2021 at "Translational pediatrics"
DOI: 10.21037/tp-21-68
Abstract: Background Cystic fibrosis (CF) is a multi-organ genetic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene which encodes the CFTR protein. CF-associated liver disease (CFLD) is a common complication; diagnosis… read more here.
Keywords: cystic fibrosis; cfld; liver disease; non invasive ... See more keywords