Deconvolution of Human Urine across the Transcriptome and Metabolome
Sign Up to like & getrecommendations! Published in 2024 at "Clinical chemistry"
DOI: 10.1093/clinchem/hvae137
Abstract: BACKGROUND: Early detection of the cell type changes underlying several genitourinary tract diseases largely remains an unmet clinical need, where existing assays, if available, lack the cellular resolution afforded by an invasive biopsy. While messenger… read more here.
Keywords: cfrna; human urine; cell; metabolome ... See more keywords
Urine Cell-Free RNA vs Plasma Cell-Free RNA for Monitoring of Kidney Injury and Immune Complications
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DOI: 10.1093/clinchem/hvaf082
Abstract: Abstract Background There is increasing interest in the use of circulating cell-free RNA (cfRNA) in plasma as an analyte for diagnosing and monitoring disease. While it is known that cfRNA can also be isolated from… read more here.
Keywords: cfrna; cell free; free rna; cell ... See more keywords
Exploring the Cell-Free Transcriptome As Biomarker Source in IgM Gammopathies: New Insights from the Fondazione Italiana Linfomi “BIO-WM” Trial
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DOI: 10.1182/blood-2024-198382
Abstract: Introduction IgM gammopathies encompass a heterogeneous group of hematological conditions, ranging from IgM monoclonal gammopathies of uncertain significance (IgM-MGUS) to asymptomatic Waldenström's Macroglobulinemia (aWM) and symptomatic WM (WM). This study aimed to investigate the potential… read more here.
Keywords: cfrna; cell free; igm mgus; igm ... See more keywords
Clonotype-Naïve Detection of Clonality in Patients Suspected of Having Multiple Myeloma or Monoclonal Gammopathy Using Peripheral Blood Cell-Free RNA (cfRNA)
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DOI: 10.1182/blood-2024-201810
Abstract: Introduction: Detection of B-cell clonality in tissue and in cell-free DNA (cfDNA) has been used in various types of lymphoma and multiple myeloma (MM). However, there is no data on using cell-free RNA (cfRNA) in… read more here.
Keywords: peripheral blood; cfrna; cell; clonality ... See more keywords
Exploring the potential of cell-free RNA and Pyramid Scene Parsing Network for early preeclampsia screening
Sign Up to like & getrecommendations! Published in 2025 at "BMC Pregnancy and Childbirth"
DOI: 10.1186/s12884-025-07503-5
Abstract: Circulating cell-free RNA (cfRNA) is gaining recognition as an effective biomarker for the early detection of preeclampsia (PE). However, the current methods for selecting disease-specific biomarkers are often inefficient and typically one-dimensional. This study introduces… read more here.
Keywords: cfrna; cell free; pyramid scene; free rna ... See more keywords
Correlation between circulating cell-free RNA biomarkers and response during combination immunotherapy in previously refractory metastatic TNBC patients.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e14027
Abstract: e14027 Background: A commercial liquid biopsy test was included as an exploratory component of an integrated immunotherapy clinical trial in previously refractory metastatic TNBC patients, combining innate, high-affinity natural killer cell (haNK) therapy with adenoviral… read more here.
Keywords: tumor size; combination immunotherapy; cfrna; response ... See more keywords
A Multiplex Thyroid-Specific Assay for Quantification of Circulating Thyroid Cell-Free RNA in Plasma of Thyroid Cancer Patients
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.721832
Abstract: Background The standard of care for thyroid cancer management is thyroidectomy and adjuvant radioactive iodine (RAI). There is a paucity of clinical tool that quantifies residual thyroid volume reliably for precise adjuvant RAI dosing. Serum… read more here.
Keywords: cfrna; cell free; thyroid cancer; thyroid specific ... See more keywords