Glucocorticoid receptor DNA methylation and childhood trauma in chronic fatigue syndrome patients.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of psychosomatic research"
DOI: 10.1016/j.jpsychores.2017.11.011
Abstract: OBJECTIVE Although the precise mechanisms are not yet understood, previous studies have suggested that chronic fatigue syndrome (CFS) is associated with hypothalamic-pituitary-adrenal (HPA) axis dysregulation and trauma in early childhood. Consistent with findings suggesting that… read more here.
Keywords: childhood trauma; methylation; dna methylation; cfs patients ... See more keywords
Decreased NO production in endothelial cells exposed to plasma from ME/CFS patients.
Sign Up to like & getrecommendations! Published in 2022 at "Vascular pharmacology"
DOI: 10.1016/j.vph.2022.106953
Abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease characterized by severe and persistent fatigue. Along with clinical studies showing endothelial dysfunction (ED) in a subset of ME/CFS patients, we have recently reported altered ED-related… read more here.
Keywords: plasma cfs; cfs; cfs patients; decreased production ... See more keywords
Evidence of altered cardiac autonomic regulation in myalgic encephalomyelitis/chronic fatigue syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000017600
Abstract: Abstract Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex condition with no reliable diagnostic biomarkers. Studies have shown evidence of autonomic dysfunction in patients with ME/CFS, but results have been equivocal. Heart rate (HR)… read more here.
Keywords: chronic fatigue; cfs patients; fatigue syndrome; encephalomyelitis chronic ... See more keywords
Validation of impaired Transient Receptor Potential Melastatin 3 ion channel activity in natural killer cells from Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis patients
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Medicine"
DOI: 10.1186/s10020-019-0083-4
Abstract: BackgroundChronic Fatigue Syndrome/ Myalgic Encephalomyelitis (CFS/ME) is a complex multifactorial disorder of unknown cause having multi-system manifestations. Although the aetiology of CFS/ME remains elusive, immunological dysfunction and more particularly reduced cytotoxic activity in natural killer… read more here.
Keywords: trpm3; cfs; cfs patients; pregnenolone sulfate ... See more keywords
Sex-specific plasma lipid profiles of ME/CFS patients and their association with pain, fatigue, and cognitive symptoms
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-021-03035-6
Abstract: Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex illness which disproportionally affects females. This illness is associated with immune and metabolic perturbations that may be influenced by lipid metabolism. We therefore hypothesized that plasma… read more here.
Keywords: cfs; fatigue cognitive; sex specific; cfs patients ... See more keywords
Reduced glycolytic reserve in isolated natural killer cells from Myalgic encephalomyelitis/chronic fatigue syndrome patients: A preliminary investigation.
Sign Up to like & getrecommendations! Published in 2018 at "Asian Pacific journal of allergy and immunology"
DOI: 10.12932/ap-011117-0188
Abstract: BACKGROUND Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is medically unexplained post-exertional fatigue associated with significant reduction in natural killer cell (NK) cytotoxicity activity. Cytotoxic activity relies on glycolytic flux and mitochondrial respiration to fulfill energetic cellular… read more here.
Keywords: fatigue; cells cfs; myalgic encephalomyelitis; glycolytic reserve ... See more keywords
Novel characterisation of mast cell phenotypes from peripheral blood mononuclear cells in chronic fatigue syndrome/myalgic encephalomyelitis patients.
Sign Up to like & getrecommendations! Published in 2017 at "Asian Pacific journal of allergy and immunology"
DOI: 10.12932/ap0771
Abstract: BACKGROUND Mast cells (MCs) mediate inflammation through neuropeptides and cytokines, along with histamine and reactive oxygen species (ROS). Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is an illness characterized by an unexplained disabling fatigue with multiple physiological… read more here.
Keywords: healthy controls; cfs; cfs patients; mast cell ... See more keywords
Whole blood human transcriptome and virome analysis of ME/CFS patients experiencing post-exertional malaise following cardiopulmonary exercise testing
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0212193
Abstract: Myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) is a syndrome of unknown etiology characterized by profound fatigue exacerbated by physical activity, also known as post-exertional malaise (PEM). Previously, we did not detect evidence of immune… read more here.
Keywords: exertional malaise; cfs; cardiopulmonary exercise; cfs patients ... See more keywords
Tai Chi increases functional connectivity and decreases chronic fatigue syndrome: A pilot intervention study with machine learning and fMRI analysis
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0278415
Abstract: Background The latest guidance on chronic fatigue syndrome (CFS) recommends exercise therapy. Tai Chi, an exercise method in traditional Chinese medicine, is reportedly helpful for CFS. However, the mechanism remains unclear. The present longitudinal study… read more here.
Keywords: cfs patients; tai chi; tai; chi exercise ... See more keywords
Endothelial dysfunction in ME/CFS patients
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DOI: 10.1371/journal.pone.0280942
Abstract: Objective A few earlier studies have found impaired endothelial function in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The present study investigated large-vessel and small-vessel endothelial function in patients with ME/CFS. Study design The study… read more here.
Keywords: porh; function; endothelial function; cfs patients ... See more keywords
Cellular Immune Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.00796
Abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating condition with unknown aetiology, Myalgic encephalomyelitis unclear pathophysiology and with no diagnostic test or biomarker available. Many patients report their ME/CFS began after an acute infection, and… read more here.
Keywords: cfs; encephalomyelitis chronic; myalgic encephalomyelitis; cfs patients ... See more keywords