CFTR expression decreases with age in several airway cell types
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-80108-8
Abstract: The mucociliary clearance (MC) system is a vital host defense against infection in the lung. MC system function is dependent on ciliary density, structure, and function and airway surface liquid (ASL) composition and hydration. Animal… read more here.
Keywords: expression; cftr expression; decreases age; expression decreases ... See more keywords
The relationship between CFTR expression and cAMP-stimulated bicarbonate secretion diverges for the duodenum and ileum of pig
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733469
Abstract: The luminal pH of the small intestine influences the digestion and absorption of nutrients. HCO3– secretion from Brunner’s glands and the ampulla of Vater initially alkalinize the acidic chyme upon entering the small intestine, and… read more here.
Keywords: cftr pigs; cftr; hco3 secretion; secretion ... See more keywords
Naringenin Regulates CFTR Activation and Expression in Airway Epithelial Cells
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000485419
Abstract: Background/Aims: Sputum symptoms are commonly seen in the elderly. This study aimed to identify an efficacious expectorant treatment stratagem through evaluating the secretion-promoting activation and cystic fibrosis transmembrane conductance regulator (CFTR) expression of the bioactive… read more here.
Keywords: epithelial cells; cftr expression; camp content; expression ... See more keywords
Biphasic regulation of CFTR expression by ENaC in epithelial cells: The involvement of Ca2+-modulated cAMP production
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.781762
Abstract: The regulatory interaction between two typical epithelial ion channels, cystic fibrosis transmembrane conductance regulator (CFTR) and the epithelial sodium channel (ENaC), for epithelial homeostasis has been noted, although the underlying mechanisms remain unclear. Here, we… read more here.
Keywords: enac knockdown; cftr expression; ca2; expression ... See more keywords