Spatial covariance analysis reveals the residue-by-residue thermodynamic contribution of variation to the CFTR fold.
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DOI: 10.1038/s42003-022-03302-2
Abstract: Although the impact of genome variation on the thermodynamic properties of function on the protein fold has been studied in vitro, it remains a challenge to assign these relationships across the entire polypeptide sequence in… read more here.
Keywords: biology; cftr fold; variation; residue residue ... See more keywords