Sign Up to like & get
recommendations!
2
Published in 2023 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.202211-2096oc
Abstract: Rationale: Type 2 inflammation has been described in people with cystic fibrosis (CF). Whether loss of cystic fibrosis transmembrane conductance regulator (CFTR) function contributes directly to a type 2 inflammatory response has not been fully…
read more here.
Keywords:
inflammation;
cftr mice;
cftr;
release ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.868863
Abstract: Introduction: Severity and disease progression in people with Cystic Fibrosis (CF) is typically dependent on their genotype. One potential therapeutic strategy for people with specific mutations is exon skipping with antisense oligonucleotides (AO). CFTR exon…
read more here.
Keywords:
cftr mice;
cftr exon;
model;
exon skipping ... See more keywords
Sign Up to like & get
recommendations!
2
Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179993
Abstract: Mutations in the CFTR chloride channel result in intestinal obstructive episodes in cystic fibrosis (CF) patients and in CF animal models. In this study, we explored the possibility of reducing the frequency of obstructive episodes…
read more here.
Keywords:
cftr mice;
tenapanor;
nhe3 inhibitor;
mice ... See more keywords